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- W2078644986 abstract "The action spectra of five eukaryotic organisms and the prokaryote, Escherichia coli, were examined over the wavelength range, 254-320 nm. Both the repair competent and three repair defective strains (E. coli, Caenorhabditis elegans, Saccharomyces) were examined. Tetrahymena pyriformis action spectra were performed with and without the excision repair inhibitor caffeine present. Others have observed that lethality, mutation, and the production of pyrimidine dimers show much the same wavelength dependence as DNA absorption. The results presented here demonstrate several action spectra which deviate from the DNA absorption spectra. Ultraviolet sensitization ratios (repair competent/repair defective) were also examined and were shown to change over the wavelength range. These findings suggest that DNA may not be the only important chromophore leading to cell death in the uv wavelength range studied. Since uv-B is of major importance in solar uv damage, these findings may also yield important implications for solar uv studies." @default.
- W2078644986 created "2016-06-24" @default.
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- W2078644986 date "1988-05-01" @default.
- W2078644986 modified "2023-09-25" @default.
- W2078644986 title "Comparative Ultraviolet Action Spectra (254-320 nm) of Five Wild-Type Eukaryotic Microorganisms and Escherichia coli" @default.
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- W2078644986 doi "https://doi.org/10.2307/3577227" @default.
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