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- W2078651644 abstract "The value of an extract of Hypericum perforatum (St John's wort) for children with mild to moderate depressive symptoms was investigated for the first time in a multi-centre post-marketing surveillance study. One hundred and one children under 12 years were treated for a minimum of 4 weeks with an extension to 6 weeks with parental consent and medical practitioner recommendation. the dosage used ranged from 300 to 1800 mg per day. Compliance, tolerability and efficacy were assessed every 2 weeks by physicians and parents. Based on the data available for analysis, the number of physicians rating effectiveness as 'good' or 'excellent' was 72% after 2 weeks, 97% after 4 weeks and 100% after 6 weeks. The ratings by parents were very similar. There was, however, an increasing amount of missing data at each assessment point with the final evaluation including only 76% of the initial sample. Tolerability was good and no adverse events were reported. The results of this study suggest that Hypericum is a potentially safe and effective treatment for children with symptoms of depression." @default.
- W2078651644 created "2016-06-24" @default.
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- W2078651644 date "2001-06-01" @default.
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- W2078651644 title "Experience with St John's Wort (<i>Hypericum perforatum</i>) in children under 12 years with symptoms of depression and psychovegetative disturbances" @default.
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- W2078651644 doi "https://doi.org/10.1002/ptr.829" @default.
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