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- W2078656847 abstract "Pure red cell aplasia (PRCA) is a rare, refractory auto-immune disease, and produces chronic progressive anemia because of a failure of erythropoiesis. Half the patients with PRCA are associated with thymoma. Thymo-thymectomy is not sufficient to restore the hemopoiesis in this disease. This time we experienced a rare patient with PRCA associated with a thymoma who was able to get an alleviation of the disease by thymo-thymectomy for the thymoma. A 58-year-old female was admitted to the hospital because of shortness of breath on excersize and palpitation. There was a remarkable anemia. Reticulocyte was not noted in the complete blood count, and also a bone marrow aspiration revealed few erythroblasts. CT scanning revealed an anterior mediastinal tumor. Under a diagnosis of thymoma with PRCA, drug therapy with steroids was started. It was a useful treatment, but the effective dosage of steroids was controversial. Thymo-thymectomy was performed. Histological diagnosis of spindle-cell thymoma with no invasive growth out of the capsule was made. After the operation, prednisolone 25mg with cyclospoline 25mg followed by prednisolone 5mg as the maintenance dose successfully provided a marked improvement of anemia." @default.
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- W2078656847 date "1995-01-01" @default.
- W2078656847 modified "2023-10-02" @default.
- W2078656847 title "AN OPERATED CASE OF THYMOMA WITH PURE RED CELL APLASIA" @default.
- W2078656847 cites W2017375283 @default.
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- W2078656847 doi "https://doi.org/10.3919/ringe1963.56.1142" @default.
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