FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078657302> ?p ?o ?g. }

• W2078657302 endingPage "165" @default.
• W2078657302 startingPage "158" @default.
• W2078657302 abstract "To determine the frequency and clinical significance of acquired abnormalities of chromosome 3 at q21 and q25-26 in haematological malignancy, we reviewed the haematological and cytogenetic features of 24 patients with a 3q rearrangement identified amongst 1200 cases with clonal cytogenetic abnormalities detected at our institutions during a 12-year period. Thirteen patients presented with de novo acute myeloid leukaemia (AML), 10 with myelodysplasia (MDS) and one in blast phase of chronic myelogenous leukaemia. Twenty patients (83%) had megakaryocytic dysplasia and 14 (58%) had normal or increased numbers of megakaryocytes, but only four patients (16%) had absolute thrombocytosis > 500 x 10(9)/l (three with AML, one with MDS transforming to AML). A review of 205 cases of AML investigated in our institutions between 1985 and 1990 for whom cytogenetic results were obtained revealed that a platelet count > 500 x 10(9)/l at presentation was highly suggestive of an underlying 3q abnormality. A limited review of the literature on this subject confirmed that 15-20% of patients with a 3q abnormality will have thrombocytosis. The response of these patients to conventional antileukaemic therapy is uniformly poor, despite haematological and clinical differences between the subtypes of 3q rearrangements." @default.
• W2078657302 created "2016-06-24" @default.
• W2078657302 creator A5009025511 @default.
• W2078657302 creator A5052579606 @default.
• W2078657302 creator A5071626502 @default.
• W2078657302 creator A5090559016 @default.
• W2078657302 date "1993-01-01" @default.
• W2078657302 modified "2023-09-23" @default.
• W2078657302 title "Clinical, haematological and cytogenetic features in 24 patients with structural rearrangements of the Q arm of chromosome 3" @default.
• W2078657302 cites W1918856651 @default.
• W2078657302 cites W1969141341 @default.
• W2078657302 cites W1993071663 @default.
• W2078657302 cites W1998329559 @default.
• W2078657302 cites W2002966604 @default.
• W2078657302 cites W2013309598 @default.
• W2078657302 cites W2025484402 @default.
• W2078657302 cites W2069621605 @default.
• W2078657302 cites W2087644365 @default.
• W2078657302 cites W2093224856 @default.
• W2078657302 cites W2106493687 @default.
• W2078657302 cites W2147213204 @default.
• W2078657302 cites W2150113701 @default.
• W2078657302 cites W2275994791 @default.
• W2078657302 cites W2364667991 @default.
• W2078657302 cites W2404827353 @default.
• W2078657302 cites W2417381454 @default.
• W2078657302 cites W2417547808 @default.
• W2078657302 cites W2470741139 @default.
• W2078657302 cites W4236296592 @default.
• W2078657302 cites W4253916874 @default.
• W2078657302 doi "https://doi.org/10.1111/j.1365-2141.1993.tb04647.x" @default.
• W2078657302 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8435325" @default.
• W2078657302 hasPublicationYear "1993" @default.
• W2078657302 type Work @default.
• W2078657302 sameAs 2078657302 @default.
• W2078657302 citedByCount "68" @default.
• W2078657302 countsByYear W20786573022012 @default.
• W2078657302 countsByYear W20786573022013 @default.
• W2078657302 countsByYear W20786573022014 @default.
• W2078657302 countsByYear W20786573022015 @default.
• W2078657302 countsByYear W20786573022016 @default.
• W2078657302 countsByYear W20786573022017 @default.
• W2078657302 countsByYear W20786573022019 @default.
• W2078657302 countsByYear W20786573022020 @default.
• W2078657302 countsByYear W20786573022021 @default.
• W2078657302 countsByYear W20786573022023 @default.
• W2078657302 crossrefType "journal-article" @default.
• W2078657302 hasAuthorship W2078657302A5009025511 @default.
• W2078657302 hasAuthorship W2078657302A5052579606 @default.
• W2078657302 hasAuthorship W2078657302A5071626502 @default.
• W2078657302 hasAuthorship W2078657302A5090559016 @default.
• W2078657302 hasConcept C104317684 @default.
• W2078657302 hasConcept C118552586 @default.
• W2078657302 hasConcept C126322002 @default.
• W2078657302 hasConcept C142724271 @default.
• W2078657302 hasConcept C174475383 @default.
• W2078657302 hasConcept C2775894508 @default.
• W2078657302 hasConcept C2778461978 @default.
• W2078657302 hasConcept C2779282312 @default.
• W2078657302 hasConcept C2779399171 @default.
• W2078657302 hasConcept C2779788118 @default.
• W2078657302 hasConcept C2780189214 @default.
• W2078657302 hasConcept C2780506209 @default.
• W2078657302 hasConcept C2910729011 @default.
• W2078657302 hasConcept C30481170 @default.
• W2078657302 hasConcept C50965678 @default.
• W2078657302 hasConcept C53226629 @default.
• W2078657302 hasConcept C54355233 @default.
• W2078657302 hasConcept C71924100 @default.
• W2078657302 hasConcept C86803240 @default.
• W2078657302 hasConcept C89560881 @default.
• W2078657302 hasConcept C90924648 @default.
• W2078657302 hasConceptScore W2078657302C104317684 @default.
• W2078657302 hasConceptScore W2078657302C118552586 @default.
• W2078657302 hasConceptScore W2078657302C126322002 @default.
• W2078657302 hasConceptScore W2078657302C142724271 @default.
• W2078657302 hasConceptScore W2078657302C174475383 @default.
• W2078657302 hasConceptScore W2078657302C2775894508 @default.
• W2078657302 hasConceptScore W2078657302C2778461978 @default.
• W2078657302 hasConceptScore W2078657302C2779282312 @default.
• W2078657302 hasConceptScore W2078657302C2779399171 @default.
• W2078657302 hasConceptScore W2078657302C2779788118 @default.
• W2078657302 hasConceptScore W2078657302C2780189214 @default.
• W2078657302 hasConceptScore W2078657302C2780506209 @default.
• W2078657302 hasConceptScore W2078657302C2910729011 @default.
• W2078657302 hasConceptScore W2078657302C30481170 @default.
• W2078657302 hasConceptScore W2078657302C50965678 @default.
• W2078657302 hasConceptScore W2078657302C53226629 @default.
• W2078657302 hasConceptScore W2078657302C54355233 @default.
• W2078657302 hasConceptScore W2078657302C71924100 @default.
• W2078657302 hasConceptScore W2078657302C86803240 @default.
• W2078657302 hasConceptScore W2078657302C89560881 @default.
• W2078657302 hasConceptScore W2078657302C90924648 @default.
• W2078657302 hasIssue "1" @default.
• W2078657302 hasLocation W20786573021 @default.
• W2078657302 hasLocation W20786573022 @default.
• W2078657302 hasOpenAccess W2078657302 @default.
• W2078657302 hasPrimaryLocation W20786573021 @default.

• next