FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078658531> ?p ?o ?g. }

• W2078658531 endingPage "7063" @default.
• W2078658531 startingPage "7058" @default.
• W2078658531 abstract "Genomic islands, large potentially mobile regions of bacterial chromosomes, are a major contributor to bacteria evolution. Here, we investigated the fitness cost and phenotypic differences between the bacterium Pseudomonas aeruginosa PAO1 and a derivative carrying one integrated copy of the clc element, a 103-kb genomic island [and integrative and conjugative element (ICE)] originating in Pseudomonas sp. strain B13 and a close relative of genomic islands found in clinical and environmental isolates of P. aeruginosa . By using a combination of whole genome transcriptome profiling, phenotypic arrays, competition experiments, and biofilm formation studies, only few differences became apparent, such as reduced biofilm growth and fourfold stationary phase repression of genes involved in acetoin metabolism in PAO1 containing the clc element. In contrast, PAO1 carrying the clc element acquired the capacity to grow on 3-chlorobenzoate and 2-aminophenol as sole carbon and energy substrates. No fitness loss >1% was detectable in competition experiments between PAO1 and PAO1 carrying the clc element. The genes from the clc element were not silent in PAO1, and excision was observed, although transfer of clc from PAO1 to other recipient bacteria was reduced by two orders of magnitude. Our results indicate that newly acquired mobile DNA not necessarily invoke an important fitness cost on their host. Absence of immediate detriment to the host may have contributed to the wide distribution of genomic islands like clc in bacterial genomes." @default.
• W2078658531 created "2016-06-24" @default.
• W2078658531 creator A5059280249 @default.
• W2078658531 creator A5066057495 @default.
• W2078658531 creator A5076689964 @default.
• W2078658531 creator A5084105383 @default.
• W2078658531 creator A5085950816 @default.
• W2078658531 date "2008-05-13" @default.
• W2078658531 modified "2023-10-11" @default.
• W2078658531 title "Host and invader impact of transfer of the <i>clc</i> genomic island into <i>Pseudomonas aeruginosa</i> PAO1" @default.
• W2078658531 cites W1501812222 @default.
• W2078658531 cites W1763885810 @default.
• W2078658531 cites W1895949598 @default.
• W2078658531 cites W1953109925 @default.
• W2078658531 cites W1968146772 @default.
• W2078658531 cites W1968885027 @default.
• W2078658531 cites W1994670764 @default.
• W2078658531 cites W1995025557 @default.
• W2078658531 cites W2009715778 @default.
• W2078658531 cites W2014456513 @default.
• W2078658531 cites W2034279867 @default.
• W2078658531 cites W2045765967 @default.
• W2078658531 cites W2055825464 @default.
• W2078658531 cites W2061539278 @default.
• W2078658531 cites W2073162392 @default.
• W2078658531 cites W2090716796 @default.
• W2078658531 cites W2102601964 @default.
• W2078658531 cites W2107921573 @default.
• W2078658531 cites W2108332051 @default.
• W2078658531 cites W2111676640 @default.
• W2078658531 cites W2122487853 @default.
• W2078658531 cites W2126115772 @default.
• W2078658531 cites W2133300547 @default.
• W2078658531 cites W2138391026 @default.
• W2078658531 cites W2138952930 @default.
• W2078658531 cites W2157838468 @default.
• W2078658531 cites W2171948544 @default.
• W2078658531 doi "https://doi.org/10.1073/pnas.0801269105" @default.
• W2078658531 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2383934" @default.
• W2078658531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18448680" @default.
• W2078658531 hasPublicationYear "2008" @default.
• W2078658531 type Work @default.
• W2078658531 sameAs 2078658531 @default.
• W2078658531 citedByCount "61" @default.
• W2078658531 countsByYear W20786585312012 @default.
• W2078658531 countsByYear W20786585312013 @default.
• W2078658531 countsByYear W20786585312014 @default.
• W2078658531 countsByYear W20786585312015 @default.
• W2078658531 countsByYear W20786585312016 @default.
• W2078658531 countsByYear W20786585312017 @default.
• W2078658531 countsByYear W20786585312018 @default.
• W2078658531 countsByYear W20786585312019 @default.
• W2078658531 countsByYear W20786585312020 @default.
• W2078658531 countsByYear W20786585312021 @default.
• W2078658531 countsByYear W20786585312022 @default.
• W2078658531 countsByYear W20786585312023 @default.
• W2078658531 crossrefType "journal-article" @default.
• W2078658531 hasAuthorship W2078658531A5059280249 @default.
• W2078658531 hasAuthorship W2078658531A5066057495 @default.
• W2078658531 hasAuthorship W2078658531A5076689964 @default.
• W2078658531 hasAuthorship W2078658531A5084105383 @default.
• W2078658531 hasAuthorship W2078658531A5085950816 @default.
• W2078658531 hasBestOaLocation W20786585311 @default.
• W2078658531 hasConcept C104317684 @default.
• W2078658531 hasConcept C127716648 @default.
• W2078658531 hasConcept C132533263 @default.
• W2078658531 hasConcept C141231307 @default.
• W2078658531 hasConcept C2777637488 @default.
• W2078658531 hasConcept C2780258820 @default.
• W2078658531 hasConcept C3742359 @default.
• W2078658531 hasConcept C523546767 @default.
• W2078658531 hasConcept C54355233 @default.
• W2078658531 hasConcept C58123911 @default.
• W2078658531 hasConcept C86803240 @default.
• W2078658531 hasConcept C89423630 @default.
• W2078658531 hasConcept C92938381 @default.
• W2078658531 hasConceptScore W2078658531C104317684 @default.
• W2078658531 hasConceptScore W2078658531C127716648 @default.
• W2078658531 hasConceptScore W2078658531C132533263 @default.
• W2078658531 hasConceptScore W2078658531C141231307 @default.
• W2078658531 hasConceptScore W2078658531C2777637488 @default.
• W2078658531 hasConceptScore W2078658531C2780258820 @default.
• W2078658531 hasConceptScore W2078658531C3742359 @default.
• W2078658531 hasConceptScore W2078658531C523546767 @default.
• W2078658531 hasConceptScore W2078658531C54355233 @default.
• W2078658531 hasConceptScore W2078658531C58123911 @default.
• W2078658531 hasConceptScore W2078658531C86803240 @default.
• W2078658531 hasConceptScore W2078658531C89423630 @default.
• W2078658531 hasConceptScore W2078658531C92938381 @default.
• W2078658531 hasIssue "19" @default.
• W2078658531 hasLocation W20786585311 @default.
• W2078658531 hasLocation W20786585312 @default.
• W2078658531 hasLocation W20786585313 @default.
• W2078658531 hasLocation W20786585314 @default.
• W2078658531 hasOpenAccess W2078658531 @default.
• W2078658531 hasPrimaryLocation W20786585311 @default.
• W2078658531 hasRelatedWork W1895949598 @default.
• W2078658531 hasRelatedWork W1989898630 @default.

• next