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- W207866716 abstract "Prokaryotes can adapt to varying environmental conditions by multiple mechanisms, including transient changes in transcription, translation, and posttranslation activities or heritable changes in regulatory or coding DNA sequences. This article addresses mechanisms for high-frequency, stochastic genotypic switching that occurs at DNA regions of increased recombination or mutation, called contingency loci. The heritable DNA rearrangements or mutations that occur at contingency loci pre-adapt a subpopulation of cells for variation in their environment. The systems that are highlighted are the defining examples for control of alternation of gene expression by site-specific DNA inversion, reversible insertion of an IS element, and slipped-strand mispairing at simple sequence DNA repeats." @default.
- W207866716 created "2016-06-24" @default.
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- W207866716 date "2013-01-01" @default.
- W207866716 modified "2023-09-23" @default.
- W207866716 title "Alternation of Gene Expression" @default.
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- W207866716 doi "https://doi.org/10.1016/b978-0-12-374984-0.00042-5" @default.
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