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- W2078673902 abstract "The effects of oxotremorine in mice were prevented by l-DOPA pretreatment. When l-DOPA was given with carbidopa it abolished oxotremorine-induced catalepsy and tremor but not diarrhoea and lachrymation. When l-DOPA was given with fusaric acid it had a similar effect to l-DOPA given with carbidopa. Noradrenaline and dopamine, on the other hand, antagonized only diarrhoea and lachrymation. 5-Hydroxytryptophan was ineffective against oxotremorine. It is concluded that l-DOPA pretreatment abolished catalepsy and tremor induced by oxotremorine through a central action, whereas diarrhoea and lachrymation are prevented by noradrenaline to which l-DOPA is converted." @default.
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- W2078673902 date "1979-07-01" @default.
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- W2078673902 title "Abolition of oxotremorine effects by l-DOPA pretreatment" @default.
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- W2078673902 doi "https://doi.org/10.1016/0028-3908(79)90111-4" @default.
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