Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078682757> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2078682757 endingPage "2901" @default.
- W2078682757 startingPage "2893" @default.
- W2078682757 abstract "A human immunodeficiency virus (HIV) as a biological endpoint in HIV prevention trials may not be feasible, so investigators have used surrogate biological outcomes. In a multisite trial, the epidemiology of STIs may be different across sites and preclude using one STI as the outcome. This study explored using a composite STI outcome to address that problem. The combined biological endpoint was the incidence of any of six new STIs (chlamydia, gonorrhea, trichomonas (women only), syphilis, herpes simplex virus type 2 infection and HIV) during a 24-month follow up period. We investigated how a composite STI outcome would perform compared to single and dual STI outcomes under various conditions. We simulated outcomes for four populations that represented a wide range of sex and age distributions, and STI prevalences. The simulations demonstrated that a combined biologic outcome was superior to single and dual STI outcomes in assessing intervention effects in 82 % of the cases. A composite biological outcome was effective in detecting intervention effects and might allow more investigations to incorporate multiple biological outcomes in the assessment of behavioral intervention trials for HIV prevention." @default.
- W2078682757 created "2016-06-24" @default.
- W2078682757 creator A5000463134 @default.
- W2078682757 creator A5013604891 @default.
- W2078682757 creator A5018908097 @default.
- W2078682757 creator A5019872491 @default.
- W2078682757 creator A5032924643 @default.
- W2078682757 creator A5045421920 @default.
- W2078682757 creator A5065169034 @default.
- W2078682757 creator A5078439567 @default.
- W2078682757 creator A5091442849 @default.
- W2078682757 date "2013-06-09" @default.
- W2078682757 modified "2023-10-06" @default.
- W2078682757 title "The Utility of a Composite Biological Endpoint in HIV/STI Prevention Trials" @default.
- W2078682757 cites W1994011595 @default.
- W2078682757 cites W2009578065 @default.
- W2078682757 cites W2030566928 @default.
- W2078682757 cites W2039096157 @default.
- W2078682757 cites W2049710488 @default.
- W2078682757 cites W2093237354 @default.
- W2078682757 cites W2118452659 @default.
- W2078682757 cites W2153335467 @default.
- W2078682757 cites W2171658410 @default.
- W2078682757 cites W2795879260 @default.
- W2078682757 cites W3020882730 @default.
- W2078682757 cites W3152482163 @default.
- W2078682757 doi "https://doi.org/10.1007/s10461-013-0501-5" @default.
- W2078682757 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4157522" @default.
- W2078682757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23748863" @default.
- W2078682757 hasPublicationYear "2013" @default.
- W2078682757 type Work @default.
- W2078682757 sameAs 2078682757 @default.
- W2078682757 citedByCount "5" @default.
- W2078682757 countsByYear W20786827572015 @default.
- W2078682757 countsByYear W20786827572016 @default.
- W2078682757 countsByYear W20786827572017 @default.
- W2078682757 countsByYear W20786827572022 @default.
- W2078682757 countsByYear W20786827572023 @default.
- W2078682757 crossrefType "journal-article" @default.
- W2078682757 hasAuthorship W2078682757A5000463134 @default.
- W2078682757 hasAuthorship W2078682757A5013604891 @default.
- W2078682757 hasAuthorship W2078682757A5018908097 @default.
- W2078682757 hasAuthorship W2078682757A5019872491 @default.
- W2078682757 hasAuthorship W2078682757A5032924643 @default.
- W2078682757 hasAuthorship W2078682757A5045421920 @default.
- W2078682757 hasAuthorship W2078682757A5065169034 @default.
- W2078682757 hasAuthorship W2078682757A5078439567 @default.
- W2078682757 hasAuthorship W2078682757A5091442849 @default.
- W2078682757 hasBestOaLocation W20786827572 @default.
- W2078682757 hasConcept C120665830 @default.
- W2078682757 hasConcept C121332964 @default.
- W2078682757 hasConcept C126322002 @default.
- W2078682757 hasConcept C168563851 @default.
- W2078682757 hasConcept C203014093 @default.
- W2078682757 hasConcept C2776939746 @default.
- W2078682757 hasConcept C2776983459 @default.
- W2078682757 hasConcept C2778082588 @default.
- W2078682757 hasConcept C2779496540 @default.
- W2078682757 hasConcept C2780122209 @default.
- W2078682757 hasConcept C3013748606 @default.
- W2078682757 hasConcept C61511704 @default.
- W2078682757 hasConcept C71924100 @default.
- W2078682757 hasConceptScore W2078682757C120665830 @default.
- W2078682757 hasConceptScore W2078682757C121332964 @default.
- W2078682757 hasConceptScore W2078682757C126322002 @default.
- W2078682757 hasConceptScore W2078682757C168563851 @default.
- W2078682757 hasConceptScore W2078682757C203014093 @default.
- W2078682757 hasConceptScore W2078682757C2776939746 @default.
- W2078682757 hasConceptScore W2078682757C2776983459 @default.
- W2078682757 hasConceptScore W2078682757C2778082588 @default.
- W2078682757 hasConceptScore W2078682757C2779496540 @default.
- W2078682757 hasConceptScore W2078682757C2780122209 @default.
- W2078682757 hasConceptScore W2078682757C3013748606 @default.
- W2078682757 hasConceptScore W2078682757C61511704 @default.
- W2078682757 hasConceptScore W2078682757C71924100 @default.
- W2078682757 hasIssue "9" @default.
- W2078682757 hasLocation W20786827571 @default.
- W2078682757 hasLocation W20786827572 @default.
- W2078682757 hasLocation W20786827573 @default.
- W2078682757 hasLocation W20786827574 @default.
- W2078682757 hasOpenAccess W2078682757 @default.
- W2078682757 hasPrimaryLocation W20786827571 @default.
- W2078682757 hasRelatedWork W2438963626 @default.
- W2078682757 hasRelatedWork W2791319705 @default.
- W2078682757 hasRelatedWork W2791571617 @default.
- W2078682757 hasRelatedWork W2910554690 @default.
- W2078682757 hasRelatedWork W2992398427 @default.
- W2078682757 hasRelatedWork W3010750074 @default.
- W2078682757 hasRelatedWork W3025040915 @default.
- W2078682757 hasRelatedWork W3037931602 @default.
- W2078682757 hasRelatedWork W4226048414 @default.
- W2078682757 hasRelatedWork W4294542939 @default.
- W2078682757 hasVolume "17" @default.
- W2078682757 isParatext "false" @default.
- W2078682757 isRetracted "false" @default.
- W2078682757 magId "2078682757" @default.
- W2078682757 workType "article" @default.