FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078686642> ?p ?o ?g. }

• W2078686642 endingPage "684" @default.
• W2078686642 startingPage "681" @default.
• W2078686642 abstract "Introduction Treatment with B-vitamins and betaine reduces the high risk of thrombosis in patients with homocystinuria, a metabolic syndrome that is characterized by severe hyperhomocysteinemia (HHcy). In contrast, there is no clear demonstration that B-vitamins reduce the risk of thrombosis in patients with mild HHcy: for this reason, many question the clinical utility of measuring total Hcy (tHcy) in patients with thrombosis. However, thrombosis may be the first clinical manifestation of homocystinuria in patients reaching adulthood without signs and symptoms of the syndrome. Aim 1) to measure the prevalence of severe, previously undiagnosed, HHcy among patients with thrombosis 2) to profile these patients on the basis of their characteristics. Methods Six Italian Thrombosis Centers completed a first questionnaire, reporting tHcy levels in patients with thrombosis who underwent thrombophilia screening, and a second questionnaire, reporting the characteristics of patients with severe HHcy (tHcy > 100 μmol/L). Results Of 19,678 cross-sectionally collected patients with thrombosis who underwent thrombophilia screening in the last 12.5 years (median value, range 6-17), 38 had severe HHcy (0.2%). Their median age at diagnosis was 47 years (range 19-83) and the median level of tHcy was 130 μmol/L (range 101-262). Venous thromboembolism (71%) was more frequent than arterial thromboembolism (26%); recurrent thrombosis occurred in 42% of cases. Conclusions Measurement of tHcy in adult patients with thrombosis may reveal the presence of severe HHcy. Since treatment of patients with severe HHcy decreases the risk of thrombosis, measurement of tHcy in patients with thrombosis may prove clinically useful." @default.
• W2078686642 created "2016-06-24" @default.
• W2078686642 creator A5002616642 @default.
• W2078686642 creator A5008150148 @default.
• W2078686642 creator A5019243176 @default.
• W2078686642 creator A5019490760 @default.
• W2078686642 creator A5021199054 @default.
• W2078686642 creator A5053685451 @default.
• W2078686642 creator A5054304877 @default.
• W2078686642 creator A5060924409 @default.
• W2078686642 creator A5069119458 @default.
• W2078686642 creator A5070057174 @default.
• W2078686642 creator A5077771431 @default.
• W2078686642 creator A5084997106 @default.
• W2078686642 creator A5086743821 @default.
• W2078686642 creator A5088122908 @default.
• W2078686642 date "2013-12-01" @default.
• W2078686642 modified "2023-10-02" @default.
• W2078686642 title "Evaluation of the prevalence of severe hyperhomocysteinemia in adult patients with thrombosis who underwent screening for thrombophilia" @default.
• W2078686642 cites W1582000856 @default.
• W2078686642 cites W2013900411 @default.
• W2078686642 cites W2021836023 @default.
• W2078686642 cites W2024869670 @default.
• W2078686642 cites W2078369761 @default.
• W2078686642 cites W2087355759 @default.
• W2078686642 cites W2104630097 @default.
• W2078686642 cites W2109814387 @default.
• W2078686642 cites W2121977609 @default.
• W2078686642 cites W2124275823 @default.
• W2078686642 cites W2132982106 @default.
• W2078686642 cites W2143881211 @default.
• W2078686642 cites W2145734151 @default.
• W2078686642 cites W2230430502 @default.
• W2078686642 cites W8707819 @default.
• W2078686642 doi "https://doi.org/10.1016/j.thromres.2013.09.038" @default.
• W2078686642 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24168815" @default.
• W2078686642 hasPublicationYear "2013" @default.
• W2078686642 type Work @default.
• W2078686642 sameAs 2078686642 @default.
• W2078686642 citedByCount "15" @default.
• W2078686642 countsByYear W20786866422014 @default.
• W2078686642 countsByYear W20786866422015 @default.
• W2078686642 countsByYear W20786866422016 @default.
• W2078686642 countsByYear W20786866422017 @default.
• W2078686642 countsByYear W20786866422018 @default.
• W2078686642 countsByYear W20786866422019 @default.
• W2078686642 countsByYear W20786866422020 @default.
• W2078686642 countsByYear W20786866422021 @default.
• W2078686642 countsByYear W20786866422022 @default.
• W2078686642 crossrefType "journal-article" @default.
• W2078686642 hasAuthorship W2078686642A5002616642 @default.
• W2078686642 hasAuthorship W2078686642A5008150148 @default.
• W2078686642 hasAuthorship W2078686642A5019243176 @default.
• W2078686642 hasAuthorship W2078686642A5019490760 @default.
• W2078686642 hasAuthorship W2078686642A5021199054 @default.
• W2078686642 hasAuthorship W2078686642A5053685451 @default.
• W2078686642 hasAuthorship W2078686642A5054304877 @default.
• W2078686642 hasAuthorship W2078686642A5060924409 @default.
• W2078686642 hasAuthorship W2078686642A5069119458 @default.
• W2078686642 hasAuthorship W2078686642A5070057174 @default.
• W2078686642 hasAuthorship W2078686642A5077771431 @default.
• W2078686642 hasAuthorship W2078686642A5084997106 @default.
• W2078686642 hasAuthorship W2078686642A5086743821 @default.
• W2078686642 hasAuthorship W2078686642A5088122908 @default.
• W2078686642 hasConcept C126322002 @default.
• W2078686642 hasConcept C141071460 @default.
• W2078686642 hasConcept C185592680 @default.
• W2078686642 hasConcept C187212893 @default.
• W2078686642 hasConcept C2776523773 @default.
• W2078686642 hasConcept C2777090595 @default.
• W2078686642 hasConcept C2779375456 @default.
• W2078686642 hasConcept C2780011451 @default.
• W2078686642 hasConcept C2780842393 @default.
• W2078686642 hasConcept C2780868729 @default.
• W2078686642 hasConcept C2780912031 @default.
• W2078686642 hasConcept C515207424 @default.
• W2078686642 hasConcept C55493867 @default.
• W2078686642 hasConcept C71924100 @default.
• W2078686642 hasConcept C90924648 @default.
• W2078686642 hasConceptScore W2078686642C126322002 @default.
• W2078686642 hasConceptScore W2078686642C141071460 @default.
• W2078686642 hasConceptScore W2078686642C185592680 @default.
• W2078686642 hasConceptScore W2078686642C187212893 @default.
• W2078686642 hasConceptScore W2078686642C2776523773 @default.
• W2078686642 hasConceptScore W2078686642C2777090595 @default.
• W2078686642 hasConceptScore W2078686642C2779375456 @default.
• W2078686642 hasConceptScore W2078686642C2780011451 @default.
• W2078686642 hasConceptScore W2078686642C2780842393 @default.
• W2078686642 hasConceptScore W2078686642C2780868729 @default.
• W2078686642 hasConceptScore W2078686642C2780912031 @default.
• W2078686642 hasConceptScore W2078686642C515207424 @default.
• W2078686642 hasConceptScore W2078686642C55493867 @default.
• W2078686642 hasConceptScore W2078686642C71924100 @default.
• W2078686642 hasConceptScore W2078686642C90924648 @default.
• W2078686642 hasIssue "6" @default.
• W2078686642 hasLocation W20786866421 @default.
• W2078686642 hasLocation W20786866422 @default.
• W2078686642 hasOpenAccess W2078686642 @default.

• next