FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078692756> ?p ?o ?g. }

• W2078692756 endingPage "e74431" @default.
• W2078692756 startingPage "e74431" @default.
• W2078692756 abstract "Fetal brain development involves the development of the neuro-vegetative (autonomic) control that is mediated by the autonomic nervous system (ANS). Disturbances of the fetal brain development have implications for diseases in later postnatal life. In that context, the fetal functional brain age can be altered. Universal principles of developmental biology applied to patterns of autonomic control may allow a functional age assessment. The work aims at the development of a fetal autonomic brain age score (fABAS) based on heart rate patterns. We analysed n = 113 recordings in quiet sleep, n = 286 in active sleep, and n = 29 in active awakeness from normals. We estimated fABAS from magnetocardiographic recordings (21.4-40.3 weeks of gestation) preclassified in quiet sleep (n = 113, 63 females) and active sleep (n = 286, 145 females) state by cross-validated multivariate linear regression models in a cross-sectional study. According to universal system developmental principles, we included indices that address increasing fluctuation range, increasing complexity, and pattern formation (skewness, power spectral ratio VLF/LF, pNN5). The resulting models constituted fABAS. fABAS explained 66/63% (coefficient of determination R(2) of training and validation set) of the variance by age in quiet, while 51/50% in active sleep. By means of a logistic regression model using fluctuation range and fetal age, quiet and active sleep were automatically reclassified (94.3/93.1% correct classifications). We did not find relevant gender differences. We conclude that functional brain age can be assessed based on universal developmental indices obtained from autonomic control patterns. fABAS reflect normal complex functional brain maturation. The presented normative data are supplemented by an explorative study of 19 fetuses compromised by intrauterine growth restriction. We observed a shift in the state distribution towards active awakeness. The lower WGA dependent fABAS values found in active sleep may reflect alterations in the universal developmental indices, namely fluctuation amplitude, complexity, and pattern formation that constitute fABAS." @default.
• W2078692756 created "2016-06-24" @default.
• W2078692756 creator A5016603751 @default.
• W2078692756 creator A5021575338 @default.
• W2078692756 creator A5022810762 @default.
• W2078692756 creator A5049954216 @default.
• W2078692756 creator A5051985200 @default.
• W2078692756 creator A5064818699 @default.
• W2078692756 creator A5090457664 @default.
• W2078692756 date "2013-09-18" @default.
• W2078692756 modified "2023-10-14" @default.
• W2078692756 title "Fetal Functional Brain Age Assessed from Universal Developmental Indices Obtained from Neuro-Vegetative Activity Patterns" @default.
• W2078692756 cites W106975869 @default.
• W2078692756 cites W134271320 @default.
• W2078692756 cites W134933581 @default.
• W2078692756 cites W1964510906 @default.
• W2078692756 cites W1964607034 @default.
• W2078692756 cites W1982345151 @default.
• W2078692756 cites W1983159739 @default.
• W2078692756 cites W1988296064 @default.
• W2078692756 cites W2003709348 @default.
• W2078692756 cites W2003904116 @default.
• W2078692756 cites W2018298622 @default.
• W2078692756 cites W2029702814 @default.
• W2078692756 cites W2033913962 @default.
• W2078692756 cites W2037679805 @default.
• W2078692756 cites W2044976213 @default.
• W2078692756 cites W2048761108 @default.
• W2078692756 cites W2054208997 @default.
• W2078692756 cites W2069372755 @default.
• W2078692756 cites W2071451698 @default.
• W2078692756 cites W2075442821 @default.
• W2078692756 cites W2080630937 @default.
• W2078692756 cites W2086891095 @default.
• W2078692756 cites W2093266575 @default.
• W2078692756 cites W2101153618 @default.
• W2078692756 cites W2106490849 @default.
• W2078692756 cites W2118183148 @default.
• W2078692756 cites W2119492403 @default.
• W2078692756 cites W2131803478 @default.
• W2078692756 cites W2133570858 @default.
• W2078692756 cites W2161930455 @default.
• W2078692756 cites W2167145205 @default.
• W2078692756 cites W2221831393 @default.
• W2078692756 cites W2285072859 @default.
• W2078692756 cites W2322789830 @default.
• W2078692756 cites W4231516052 @default.
• W2078692756 doi "https://doi.org/10.1371/journal.pone.0074431" @default.
• W2078692756 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3776847" @default.
• W2078692756 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24058564" @default.
• W2078692756 hasPublicationYear "2013" @default.
• W2078692756 type Work @default.
• W2078692756 sameAs 2078692756 @default.
• W2078692756 citedByCount "46" @default.
• W2078692756 countsByYear W20786927562013 @default.
• W2078692756 countsByYear W20786927562014 @default.
• W2078692756 countsByYear W20786927562015 @default.
• W2078692756 countsByYear W20786927562016 @default.
• W2078692756 countsByYear W20786927562017 @default.
• W2078692756 countsByYear W20786927562018 @default.
• W2078692756 countsByYear W20786927562019 @default.
• W2078692756 countsByYear W20786927562020 @default.
• W2078692756 countsByYear W20786927562021 @default.
• W2078692756 countsByYear W20786927562022 @default.
• W2078692756 countsByYear W20786927562023 @default.
• W2078692756 crossrefType "journal-article" @default.
• W2078692756 hasAuthorship W2078692756A5016603751 @default.
• W2078692756 hasAuthorship W2078692756A5021575338 @default.
• W2078692756 hasAuthorship W2078692756A5022810762 @default.
• W2078692756 hasAuthorship W2078692756A5049954216 @default.
• W2078692756 hasAuthorship W2078692756A5051985200 @default.
• W2078692756 hasAuthorship W2078692756A5064818699 @default.
• W2078692756 hasAuthorship W2078692756A5090457664 @default.
• W2078692756 hasBestOaLocation W20786927561 @default.
• W2078692756 hasConcept C126322002 @default.
• W2078692756 hasConcept C151730666 @default.
• W2078692756 hasConcept C15744967 @default.
• W2078692756 hasConcept C169760540 @default.
• W2078692756 hasConcept C172680121 @default.
• W2078692756 hasConcept C2777372248 @default.
• W2078692756 hasConcept C2777953023 @default.
• W2078692756 hasConcept C2778376644 @default.
• W2078692756 hasConcept C2779234561 @default.
• W2078692756 hasConcept C2779343474 @default.
• W2078692756 hasConcept C54355233 @default.
• W2078692756 hasConcept C71924100 @default.
• W2078692756 hasConcept C84393581 @default.
• W2078692756 hasConcept C86803240 @default.
• W2078692756 hasConceptScore W2078692756C126322002 @default.
• W2078692756 hasConceptScore W2078692756C151730666 @default.
• W2078692756 hasConceptScore W2078692756C15744967 @default.
• W2078692756 hasConceptScore W2078692756C169760540 @default.
• W2078692756 hasConceptScore W2078692756C172680121 @default.
• W2078692756 hasConceptScore W2078692756C2777372248 @default.
• W2078692756 hasConceptScore W2078692756C2777953023 @default.
• W2078692756 hasConceptScore W2078692756C2778376644 @default.
• W2078692756 hasConceptScore W2078692756C2779234561 @default.
• W2078692756 hasConceptScore W2078692756C2779343474 @default.

• next