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- W2078695706 abstract "Idiopathic crescentic glomerulonephritis is associated with a 70% to 80% incidence of end-stage renal failure. Oral corticosteroid therapy in combination with immunosuppressive agents or anticoagulants has not altered the prognosis of this disease. We have seen five adults with idiopathic crescentic glomerulonephritis and treated them with intravenous methylprednisolone. Before therapy, the average serum creatinine concentration was 7.4 ± 1.3 mg/dL (chi-square ± SEM). This value declined to 2.0 ± 0.48 mg/dL within 4 weeks. All patients continue to maintain stable renal function over an average follow-up period of 19 months (range, 1.5 to 36 months). These data suggest that a prospective controlled trial of this therapy is warranted in the management of this entity." @default.
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- W2078695706 date "1980-04-01" @default.
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- W2078695706 title "Pulse Methylprednisolone Therapy in Idiopathic, Rapidly Progressive Glomerulonephritis" @default.
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- W2078695706 doi "https://doi.org/10.7326/0003-4819-92-4-504" @default.
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