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- W2078696534 abstract "UPON activation, the Hageman factor in plasma initiates blood coagulation as well as events that lead to the release of biologically active polypeptides, called kinins. Kinins produce signs of inflammation by inducing vasodilatation, increased vascular permeability and pain.1 2 3 4 5 6 The case to be described raises an important exception to the proposal that activation of Hageman factor may be required for the formation of kinins in synovial fluids and symptoms of rheumatoid arthritis,7 8 9 10 11 for rheumatoid arthritis developed in a woman with a severe deficiency of Hageman factor.Case ReportA 43-year-old married woman was seen in January, 1967, because of acutely red, . . ." @default.
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- W2078696534 date "1972-03-09" @default.
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- W2078696534 title "Rheumatoid Arthritis in a Patient with Hageman Trait" @default.
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- W2078696534 doi "https://doi.org/10.1056/nejm197203092861009" @default.
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