FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078698519> ?p ?o ?g. }

• W2078698519 abstract "ATG-Fresenius, a purified rabbit polyclonal anti-human T-lymphocyte immunoglobulin is used for induction immunosuppression as well as prevention and treatment of acute rejection episodes among patients receiving solid organ transplants. The aim of this study was to investigate the in vitro activity of ATG-Fresenius upon immune cell adhesion, which may explain its activity to mitigate ischemia-reperfusion injury.Human vascular endothelial cells (HUVEC) and peripheral blood mononuclear cells (PBMCs) isolated from umbilical vein or peripheral blood were incubated 20 to 24 hours before analysis. HUVEC were incubated with 10 and 100 μg/mL ATG-Fresenius or reference polyclonal rabbit immunoglobulin G. Analysis of immune cell adhesion to endothelial cells was studied in cocultures of PBMCs and adherent HUVEC. Endothelial cell expression of adhesion molecules CD62E and CD54 was determined by flow cytometry. The numbers of T-, B- and natural killer cells attached to HUVEC were also determined by flow cytometry. Groups were compared using one-way analysis of variance.We showed that ATG-Fresenius binds to endothelial cells particularly activated ones expressing increased levels of E-selectin and ICAM-1. The increased binding of ATG-Fresenius to activated endothelial cells was consistent with its known binding to Intercellular Adhesion Molecule 1 (ICAM-1) and selectins. We also showed that ATG-Fresenius inhibited adhesion of prestimulated immune cells to activated endothelium.We demonstrated dose-dependent binding of ATG-Fresenius to activated endothelial cells." @default.
• W2078698519 created "2016-06-24" @default.
• W2078698519 creator A5006166774 @default.
• W2078698519 creator A5040559149 @default.
• W2078698519 creator A5058435779 @default.
• W2078698519 creator A5070720568 @default.
• W2078698519 creator A5074324424 @default.
• W2078698519 creator A5083843333 @default.
• W2078698519 date "2013-06-01" @default.
• W2078698519 modified "2023-09-26" @default.
• W2078698519 title "In Vitro Effects of ATG-Fresenius on Immune Cell Adhesion" @default.
• W2078698519 cites W127584714 @default.
• W2078698519 cites W1971917654 @default.
• W2078698519 cites W2008649437 @default.
• W2078698519 cites W2010670980 @default.
• W2078698519 cites W2026843743 @default.
• W2078698519 cites W2038868144 @default.
• W2078698519 cites W2050170216 @default.
• W2078698519 cites W2068805358 @default.
• W2078698519 cites W2073174642 @default.
• W2078698519 cites W2171136826 @default.
• W2078698519 cites W2398481157 @default.
• W2078698519 cites W2415517075 @default.
• W2078698519 cites W2440198333 @default.
• W2078698519 cites W2042258852 @default.
• W2078698519 doi "https://doi.org/10.1016/j.transproceed.2013.01.079" @default.
• W2078698519 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23769055" @default.
• W2078698519 hasPublicationYear "2013" @default.
• W2078698519 type Work @default.
• W2078698519 sameAs 2078698519 @default.
• W2078698519 citedByCount "2" @default.
• W2078698519 countsByYear W20786985192018 @default.
• W2078698519 countsByYear W20786985192020 @default.
• W2078698519 crossrefType "journal-article" @default.
• W2078698519 hasAuthorship W2078698519A5006166774 @default.
• W2078698519 hasAuthorship W2078698519A5040559149 @default.
• W2078698519 hasAuthorship W2078698519A5058435779 @default.
• W2078698519 hasAuthorship W2078698519A5070720568 @default.
• W2078698519 hasAuthorship W2078698519A5074324424 @default.
• W2078698519 hasAuthorship W2078698519A5083843333 @default.
• W2078698519 hasConcept C123012128 @default.
• W2078698519 hasConcept C134018914 @default.
• W2078698519 hasConcept C137061746 @default.
• W2078698519 hasConcept C1491633281 @default.
• W2078698519 hasConcept C153911025 @default.
• W2078698519 hasConcept C155619193 @default.
• W2078698519 hasConcept C159654299 @default.
• W2078698519 hasConcept C16224149 @default.
• W2078698519 hasConcept C199616788 @default.
• W2078698519 hasConcept C202751555 @default.
• W2078698519 hasConcept C203014093 @default.
• W2078698519 hasConcept C2776992346 @default.
• W2078698519 hasConcept C2777411675 @default.
• W2078698519 hasConcept C2777761686 @default.
• W2078698519 hasConcept C553184892 @default.
• W2078698519 hasConcept C55493867 @default.
• W2078698519 hasConcept C85789140 @default.
• W2078698519 hasConcept C86803240 @default.
• W2078698519 hasConcept C8891405 @default.
• W2078698519 hasConcept C956191 @default.
• W2078698519 hasConceptScore W2078698519C123012128 @default.
• W2078698519 hasConceptScore W2078698519C134018914 @default.
• W2078698519 hasConceptScore W2078698519C137061746 @default.
• W2078698519 hasConceptScore W2078698519C1491633281 @default.
• W2078698519 hasConceptScore W2078698519C153911025 @default.
• W2078698519 hasConceptScore W2078698519C155619193 @default.
• W2078698519 hasConceptScore W2078698519C159654299 @default.
• W2078698519 hasConceptScore W2078698519C16224149 @default.
• W2078698519 hasConceptScore W2078698519C199616788 @default.
• W2078698519 hasConceptScore W2078698519C202751555 @default.
• W2078698519 hasConceptScore W2078698519C203014093 @default.
• W2078698519 hasConceptScore W2078698519C2776992346 @default.
• W2078698519 hasConceptScore W2078698519C2777411675 @default.
• W2078698519 hasConceptScore W2078698519C2777761686 @default.
• W2078698519 hasConceptScore W2078698519C553184892 @default.
• W2078698519 hasConceptScore W2078698519C55493867 @default.
• W2078698519 hasConceptScore W2078698519C85789140 @default.
• W2078698519 hasConceptScore W2078698519C86803240 @default.
• W2078698519 hasConceptScore W2078698519C8891405 @default.
• W2078698519 hasConceptScore W2078698519C956191 @default.
• W2078698519 hasLocation W20786985191 @default.
• W2078698519 hasLocation W20786985192 @default.
• W2078698519 hasOpenAccess W2078698519 @default.
• W2078698519 hasPrimaryLocation W20786985191 @default.
• W2078698519 hasRelatedWork W1534764985 @default.
• W2078698519 hasRelatedWork W1549757852 @default.
• W2078698519 hasRelatedWork W1617255948 @default.
• W2078698519 hasRelatedWork W1982925494 @default.
• W2078698519 hasRelatedWork W2000721338 @default.
• W2078698519 hasRelatedWork W2019459054 @default.
• W2078698519 hasRelatedWork W2030844104 @default.
• W2078698519 hasRelatedWork W2036237176 @default.
• W2078698519 hasRelatedWork W2061432244 @default.
• W2078698519 hasRelatedWork W2068805358 @default.
• W2078698519 hasRelatedWork W2073785692 @default.
• W2078698519 hasRelatedWork W2101216734 @default.
• W2078698519 hasRelatedWork W2119164601 @default.
• W2078698519 hasRelatedWork W2299851596 @default.
• W2078698519 hasRelatedWork W2372353483 @default.
• W2078698519 hasRelatedWork W2380318526 @default.

• next