FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078704504> ?p ?o ?g. }

• W2078704504 endingPage "162" @default.
• W2078704504 startingPage "153" @default.
• W2078704504 abstract "Transcription of the type IV pilus subunit gene of Pseudomonas aeruginosa is controlled by a two-component signal transduction system. PilS, the histidine kinase, is membrane bound and PilR, its cognate response regulator, is cytoplasmic. The signal that activates PilS is unknown. PilS has three domains: (i) The N-terminus, predicted to form six transmembrane (TM) helices; (ii) a central linker domain; and (iii) the C-terminal transmitter domain containing all the conserved residues of sensor kinases. A translational fusion of the gfp gene (green fluorescent protein) to the 3' end of pilS was used to determine the position of PilS in the bacterial cell. Epifluorescence microscopy revealed that PilS is retained to the poles of P. aeruginosa but is distributed evenly about the membrane of Escherichia coli. Deletions of the PilS-GFP fusion revealed that the TM domain was sufficient and necessary to bring GFP to the membrane of P. aeruginosa and E. coli but was not sufficient to confine GFP to the poles. Retention to the poles of P. aeruginosa required both the TM and linker domains. Replacement of the PilS TM domain with an E. coli membrane protein, MalG, still allowed polar localization. Therefore, the PilS TM domain positions the linker domain close to the membrane allowing it to interact with the putative polar anchor which is specific to P. aeruginosa." @default.
• W2078704504 created "2016-06-24" @default.
• W2078704504 creator A5058661563 @default.
• W2078704504 date "2000-04-01" @default.
• W2078704504 modified "2023-10-13" @default.
• W2078704504 title "Localization of the histidine kinase PilS to the poles of Pseudomonas aeruginosa and identification of a localization domain" @default.
• W2078704504 cites W1485969786 @default.
• W2078704504 cites W1498681083 @default.
• W2078704504 cites W1505319357 @default.
• W2078704504 cites W1528263840 @default.
• W2078704504 cites W1563903270 @default.
• W2078704504 cites W1582323836 @default.
• W2078704504 cites W1667521611 @default.
• W2078704504 cites W1880457206 @default.
• W2078704504 cites W1915683180 @default.
• W2078704504 cites W1947156585 @default.
• W2078704504 cites W1966633139 @default.
• W2078704504 cites W1979581724 @default.
• W2078704504 cites W1985253447 @default.
• W2078704504 cites W1997440166 @default.
• W2078704504 cites W2006002169 @default.
• W2078704504 cites W2008630890 @default.
• W2078704504 cites W2016873781 @default.
• W2078704504 cites W2019410656 @default.
• W2078704504 cites W2028622989 @default.
• W2078704504 cites W2030589189 @default.
• W2078704504 cites W2043539143 @default.
• W2078704504 cites W2055824547 @default.
• W2078704504 cites W2057961335 @default.
• W2078704504 cites W2061700743 @default.
• W2078704504 cites W2071075943 @default.
• W2078704504 cites W2074329151 @default.
• W2078704504 cites W2080828561 @default.
• W2078704504 cites W2091010896 @default.
• W2078704504 cites W2098055128 @default.
• W2078704504 cites W2100670872 @default.
• W2078704504 cites W2130381741 @default.
• W2078704504 cites W2139906682 @default.
• W2078704504 cites W2142601893 @default.
• W2078704504 cites W2157336072 @default.
• W2078704504 cites W2157501876 @default.
• W2078704504 cites W2166648691 @default.
• W2078704504 cites W2460889726 @default.
• W2078704504 cites W2888511473 @default.
• W2078704504 cites W4253230027 @default.
• W2078704504 cites W4255583628 @default.
• W2078704504 doi "https://doi.org/10.1046/j.1365-2958.2000.01836.x" @default.
• W2078704504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10760172" @default.
• W2078704504 hasPublicationYear "2000" @default.
• W2078704504 type Work @default.
• W2078704504 sameAs 2078704504 @default.
• W2078704504 citedByCount "50" @default.
• W2078704504 countsByYear W20787045042012 @default.
• W2078704504 countsByYear W20787045042014 @default.
• W2078704504 countsByYear W20787045042016 @default.
• W2078704504 countsByYear W20787045042017 @default.
• W2078704504 countsByYear W20787045042020 @default.
• W2078704504 countsByYear W20787045042023 @default.
• W2078704504 crossrefType "journal-article" @default.
• W2078704504 hasAuthorship W2078704504A5058661563 @default.
• W2078704504 hasConcept C104317684 @default.
• W2078704504 hasConcept C111919701 @default.
• W2078704504 hasConcept C118892022 @default.
• W2078704504 hasConcept C123894998 @default.
• W2078704504 hasConcept C138223613 @default.
• W2078704504 hasConcept C142613039 @default.
• W2078704504 hasConcept C143065580 @default.
• W2078704504 hasConcept C170493617 @default.
• W2078704504 hasConcept C190062978 @default.
• W2078704504 hasConcept C24530287 @default.
• W2078704504 hasConcept C2776879804 @default.
• W2078704504 hasConcept C2777637488 @default.
• W2078704504 hasConcept C2778460671 @default.
• W2078704504 hasConcept C2778875234 @default.
• W2078704504 hasConcept C2778905257 @default.
• W2078704504 hasConcept C2780557392 @default.
• W2078704504 hasConcept C2781196521 @default.
• W2078704504 hasConcept C32619005 @default.
• W2078704504 hasConcept C40767141 @default.
• W2078704504 hasConcept C41008148 @default.
• W2078704504 hasConcept C41625074 @default.
• W2078704504 hasConcept C515207424 @default.
• W2078704504 hasConcept C523546767 @default.
• W2078704504 hasConcept C54355233 @default.
• W2078704504 hasConcept C55493867 @default.
• W2078704504 hasConcept C86339819 @default.
• W2078704504 hasConcept C86803240 @default.
• W2078704504 hasConcept C95444343 @default.
• W2078704504 hasConceptScore W2078704504C104317684 @default.
• W2078704504 hasConceptScore W2078704504C111919701 @default.
• W2078704504 hasConceptScore W2078704504C118892022 @default.
• W2078704504 hasConceptScore W2078704504C123894998 @default.
• W2078704504 hasConceptScore W2078704504C138223613 @default.
• W2078704504 hasConceptScore W2078704504C142613039 @default.
• W2078704504 hasConceptScore W2078704504C143065580 @default.
• W2078704504 hasConceptScore W2078704504C170493617 @default.
• W2078704504 hasConceptScore W2078704504C190062978 @default.
• W2078704504 hasConceptScore W2078704504C24530287 @default.

• next