Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078763170> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2078763170 endingPage "147" @default.
- W2078763170 startingPage "144" @default.
- W2078763170 abstract "Molecular analyses for loss of heterozygosity (LOH) at a gene locus are used to identify genomic imbalance in tumor tissue. A frequently utilized microsatellite marker for the Adenomatous Polyposis Coli (APC) gene is denoted D5S346. However, when an individual has two identical forms of this microsatellite, then a second microsatellite, also near the APC gene, is needed. We present data on an APC microsatellite marker designated D5S1385, located on the 5′ end of the APC gene, and we compare these to data utilizing the marker D5S346. Polymerase chain reaction (PCR) was used, followed by gel electrophoresis. Homozygosity for the marker D5S1385 was present in 55 individuals, or 28%. Thirty-seven carcinomas and 32 adenomas were assessed for LOH from individuals informative with both microsatellite markers. D5S1385 detected LOH in 39 of 41 lesions, or 95%, for which D5S346 detected LOH. D5S1385 is moderately polymorphic and is informative at least as often as D5S346." @default.
- W2078763170 created "2016-06-24" @default.
- W2078763170 creator A5046770257 @default.
- W2078763170 creator A5055264272 @default.
- W2078763170 creator A5057717655 @default.
- W2078763170 creator A5079576612 @default.
- W2078763170 date "2003-10-01" @default.
- W2078763170 modified "2023-09-26" @default.
- W2078763170 title "The Adenomatous Polyposis Coli (APC) gene microsatellite marker D5S1385 is equally informative for loss of heterozygosity as the marker D5S346" @default.
- W2078763170 cites W2000446801 @default.
- W2078763170 cites W2001258296 @default.
- W2078763170 cites W2092918331 @default.
- W2078763170 cites W4253321993 @default.
- W2078763170 doi "https://doi.org/10.1016/s0014-4800(03)00069-8" @default.
- W2078763170 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14516776" @default.
- W2078763170 hasPublicationYear "2003" @default.
- W2078763170 type Work @default.
- W2078763170 sameAs 2078763170 @default.
- W2078763170 citedByCount "7" @default.
- W2078763170 countsByYear W20787631702017 @default.
- W2078763170 countsByYear W20787631702020 @default.
- W2078763170 crossrefType "journal-article" @default.
- W2078763170 hasAuthorship W2078763170A5046770257 @default.
- W2078763170 hasAuthorship W2078763170A5055264272 @default.
- W2078763170 hasAuthorship W2078763170A5057717655 @default.
- W2078763170 hasAuthorship W2078763170A5079576612 @default.
- W2078763170 hasConcept C104317684 @default.
- W2078763170 hasConcept C121608353 @default.
- W2078763170 hasConcept C143589142 @default.
- W2078763170 hasConcept C153911025 @default.
- W2078763170 hasConcept C180754005 @default.
- W2078763170 hasConcept C190789776 @default.
- W2078763170 hasConcept C2777160741 @default.
- W2078763170 hasConcept C2778237340 @default.
- W2078763170 hasConcept C2779767149 @default.
- W2078763170 hasConcept C2780814781 @default.
- W2078763170 hasConcept C49105822 @default.
- W2078763170 hasConcept C526805850 @default.
- W2078763170 hasConcept C54355233 @default.
- W2078763170 hasConcept C61320498 @default.
- W2078763170 hasConcept C84597430 @default.
- W2078763170 hasConcept C86803240 @default.
- W2078763170 hasConceptScore W2078763170C104317684 @default.
- W2078763170 hasConceptScore W2078763170C121608353 @default.
- W2078763170 hasConceptScore W2078763170C143589142 @default.
- W2078763170 hasConceptScore W2078763170C153911025 @default.
- W2078763170 hasConceptScore W2078763170C180754005 @default.
- W2078763170 hasConceptScore W2078763170C190789776 @default.
- W2078763170 hasConceptScore W2078763170C2777160741 @default.
- W2078763170 hasConceptScore W2078763170C2778237340 @default.
- W2078763170 hasConceptScore W2078763170C2779767149 @default.
- W2078763170 hasConceptScore W2078763170C2780814781 @default.
- W2078763170 hasConceptScore W2078763170C49105822 @default.
- W2078763170 hasConceptScore W2078763170C526805850 @default.
- W2078763170 hasConceptScore W2078763170C54355233 @default.
- W2078763170 hasConceptScore W2078763170C61320498 @default.
- W2078763170 hasConceptScore W2078763170C84597430 @default.
- W2078763170 hasConceptScore W2078763170C86803240 @default.
- W2078763170 hasIssue "2" @default.
- W2078763170 hasLocation W20787631701 @default.
- W2078763170 hasLocation W20787631702 @default.
- W2078763170 hasOpenAccess W2078763170 @default.
- W2078763170 hasPrimaryLocation W20787631701 @default.
- W2078763170 hasRelatedWork W100798024 @default.
- W2078763170 hasRelatedWork W1986695036 @default.
- W2078763170 hasRelatedWork W1988340380 @default.
- W2078763170 hasRelatedWork W2060768610 @default.
- W2078763170 hasRelatedWork W2078763170 @default.
- W2078763170 hasRelatedWork W2124775785 @default.
- W2078763170 hasRelatedWork W2327283558 @default.
- W2078763170 hasRelatedWork W2335069950 @default.
- W2078763170 hasRelatedWork W2625931960 @default.
- W2078763170 hasRelatedWork W917883837 @default.
- W2078763170 hasVolume "75" @default.
- W2078763170 isParatext "false" @default.
- W2078763170 isRetracted "false" @default.
- W2078763170 magId "2078763170" @default.
- W2078763170 workType "article" @default.