Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078767738> ?p ?o ?g. }
- W2078767738 endingPage "422" @default.
- W2078767738 startingPage "419" @default.
- W2078767738 abstract "Generalised epilepsy and cognitive deterioration were recently described in three children following human herpesvirus 6 (HHV6)-associated post-transplant acute limbic encephalitis (PALE). Magnetic resonance imaging (MRI) showed bilateral signal change and/or atrophy in the medial temporal structures and there was no evidence of an ongoing viral or immune-mediated process. We report another child who developed this condition after cord blood transplantation for congenital neutropenia at the age of three. He presented with epileptic spasms four months after HHV6-associated PALE. Cognitive regression, prominent electroencephalographic abnormalities and different types of generalised seizures ensued during the following months and proved refractory to antiepileptic and immunomodulating treatment, which included steroids, immunoglobulin and rituximab. MRI was normal at onset of epilepsy but subsequently showed the development of right hippocampal sclerosis. Results from serial blood and cerebrospinal fluid (CSF) analyses were inconclusive, including lack of patient's CSF and serum reactivity with cultures of dissociated rat hippocampal neurons. This report confirms the existence of a new epilepsy syndrome featuring generalised seizures and epileptic encephalopathy after HHV6-associated PALE in children. Presentation with epileptic spasms, lack of CSF and serum reactivity with cultured rat hippocampal neurons, and rituximab inefficacy are novel features that contribute to delineate the syndrome and argue against an immune-mediated basis of this condition." @default.
- W2078767738 created "2016-06-24" @default.
- W2078767738 creator A5007104058 @default.
- W2078767738 creator A5030411345 @default.
- W2078767738 creator A5048193775 @default.
- W2078767738 creator A5051141975 @default.
- W2078767738 creator A5081804111 @default.
- W2078767738 creator A5089685420 @default.
- W2078767738 date "2013-08-01" @default.
- W2078767738 modified "2023-10-18" @default.
- W2078767738 title "Epileptic encephalopathy after HHV6 post-transplant acute limbic encephalitis in children: Confirmation of a new epilepsy syndrome" @default.
- W2078767738 cites W1540425213 @default.
- W2078767738 cites W1899142186 @default.
- W2078767738 cites W1980696589 @default.
- W2078767738 cites W1991120608 @default.
- W2078767738 cites W2016421065 @default.
- W2078767738 cites W2022981588 @default.
- W2078767738 cites W2023868271 @default.
- W2078767738 cites W2072624003 @default.
- W2078767738 cites W2078577955 @default.
- W2078767738 cites W2133799143 @default.
- W2078767738 cites W2146714366 @default.
- W2078767738 doi "https://doi.org/10.1016/j.eplepsyres.2013.02.019" @default.
- W2078767738 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23535036" @default.
- W2078767738 hasPublicationYear "2013" @default.
- W2078767738 type Work @default.
- W2078767738 sameAs 2078767738 @default.
- W2078767738 citedByCount "21" @default.
- W2078767738 countsByYear W20787677382014 @default.
- W2078767738 countsByYear W20787677382015 @default.
- W2078767738 countsByYear W20787677382016 @default.
- W2078767738 countsByYear W20787677382017 @default.
- W2078767738 countsByYear W20787677382018 @default.
- W2078767738 countsByYear W20787677382019 @default.
- W2078767738 countsByYear W20787677382020 @default.
- W2078767738 countsByYear W20787677382021 @default.
- W2078767738 countsByYear W20787677382023 @default.
- W2078767738 crossrefType "journal-article" @default.
- W2078767738 hasAuthorship W2078767738A5007104058 @default.
- W2078767738 hasAuthorship W2078767738A5030411345 @default.
- W2078767738 hasAuthorship W2078767738A5048193775 @default.
- W2078767738 hasAuthorship W2078767738A5051141975 @default.
- W2078767738 hasAuthorship W2078767738A5081804111 @default.
- W2078767738 hasAuthorship W2078767738A5089685420 @default.
- W2078767738 hasConcept C118552586 @default.
- W2078767738 hasConcept C126322002 @default.
- W2078767738 hasConcept C142724271 @default.
- W2078767738 hasConcept C148762608 @default.
- W2078767738 hasConcept C159654299 @default.
- W2078767738 hasConcept C187212893 @default.
- W2078767738 hasConcept C203014093 @default.
- W2078767738 hasConcept C2522874641 @default.
- W2078767738 hasConcept C2777597344 @default.
- W2078767738 hasConcept C2777699746 @default.
- W2078767738 hasConcept C2778186239 @default.
- W2078767738 hasConcept C2778201146 @default.
- W2078767738 hasConcept C2778621155 @default.
- W2078767738 hasConcept C2778734009 @default.
- W2078767738 hasConcept C2779651940 @default.
- W2078767738 hasConcept C2780653079 @default.
- W2078767738 hasConcept C2781099131 @default.
- W2078767738 hasConcept C2781172350 @default.
- W2078767738 hasConcept C71924100 @default.
- W2078767738 hasConcept C83455156 @default.
- W2078767738 hasConceptScore W2078767738C118552586 @default.
- W2078767738 hasConceptScore W2078767738C126322002 @default.
- W2078767738 hasConceptScore W2078767738C142724271 @default.
- W2078767738 hasConceptScore W2078767738C148762608 @default.
- W2078767738 hasConceptScore W2078767738C159654299 @default.
- W2078767738 hasConceptScore W2078767738C187212893 @default.
- W2078767738 hasConceptScore W2078767738C203014093 @default.
- W2078767738 hasConceptScore W2078767738C2522874641 @default.
- W2078767738 hasConceptScore W2078767738C2777597344 @default.
- W2078767738 hasConceptScore W2078767738C2777699746 @default.
- W2078767738 hasConceptScore W2078767738C2778186239 @default.
- W2078767738 hasConceptScore W2078767738C2778201146 @default.
- W2078767738 hasConceptScore W2078767738C2778621155 @default.
- W2078767738 hasConceptScore W2078767738C2778734009 @default.
- W2078767738 hasConceptScore W2078767738C2779651940 @default.
- W2078767738 hasConceptScore W2078767738C2780653079 @default.
- W2078767738 hasConceptScore W2078767738C2781099131 @default.
- W2078767738 hasConceptScore W2078767738C2781172350 @default.
- W2078767738 hasConceptScore W2078767738C71924100 @default.
- W2078767738 hasConceptScore W2078767738C83455156 @default.
- W2078767738 hasIssue "3" @default.
- W2078767738 hasLocation W20787677381 @default.
- W2078767738 hasLocation W20787677382 @default.
- W2078767738 hasOpenAccess W2078767738 @default.
- W2078767738 hasPrimaryLocation W20787677381 @default.
- W2078767738 hasRelatedWork W1993053213 @default.
- W2078767738 hasRelatedWork W2022544233 @default.
- W2078767738 hasRelatedWork W2078767738 @default.
- W2078767738 hasRelatedWork W2089104512 @default.
- W2078767738 hasRelatedWork W2312654430 @default.
- W2078767738 hasRelatedWork W2339534701 @default.
- W2078767738 hasRelatedWork W2417396913 @default.
- W2078767738 hasRelatedWork W2524115679 @default.
- W2078767738 hasRelatedWork W3124002180 @default.