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• W2078775245 abstract "The teleost fish, Oryzias curvinotus, is a closely related species to the medaka, Oryzias latipes, and both species have the DMY gene, which is required for male development in O. latipes. It suggests that the molecular function of the DMY gene and the following molecular events of sex differentiation are conserved between these two species. In the present study, we obtained interspecific hybrids between O. curvinotus and O. latipes and demonstrated sex-reversed XY females in the hybrids. The incidence of sex-reversed females in F1 XY hybrids between O. curvinotus females and O. latipes males, and hybrids between O. latipes females and O. curvinotus males were 21% and 100%, respectively. These results indicate that DMY does not always determine maleness in hybrid fish even though it is able to specify normal male development on its native genetic background and suggest that there are some differences between DMYlatipes and DMYcurvinotus alleles. Appearance of XY females in F1 hybrids also suggests that an autosomal or X-liked gene(s) from the maternal species interferes in the function of the paternal DMY gene in the male-determining process of the hybrid fish. These hybrid fish would supply a new experimental approach for investigating the genetic and molecular pathway of testis determination and differentiation. J. Exp. Zool. 305A, 2006. © 2006 Wiley-Liss, Inc." @default.
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• W2078775245 date "2006-10-01" @default.
• W2078775245 modified "2023-10-10" @default.
• W2078775245 title "Interspecific hybridization betweenOryzias latipes andOryzias curvinotus causes XY sex reversal" @default.
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• W2078775245 doi "https://doi.org/10.1002/jez.a.330" @default.
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