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• W2078789814 abstract "Metastasis, the spread of cancer in body, is a major cause of death. We have screened anti-metastatic activity of aqueous and dichloromethane extracts of several not previously studied Thai herbs, using an in vitro invasion test. This involves the in vitro invasion of HCC-S102, a hepatocellular carcinoma cell line derived from a Thai patient, through a reconstituted-basement membrane (Matrigel). The aqueous extract of a plant (Helixanthera parasitica) revealed a significant inhibitory effect on the cancer cell invasion, and showed antioxidant activity. The aqueous extract was partially purified by silica gel column chromatography, and the highest anti-metastatic activity fraction showed 83% inhibition of invasion with low cytotoxic effect. However, anti-metastatic activity was not associated with the antioxidant activity of the aqueous extract." @default.
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• W2078789814 date "2003-06-01" @default.
• W2078789814 modified "2023-10-17" @default.
• W2078789814 title "Anti-metastatic effects of aqueous extract of Helixanthera parasitica" @default.
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• W2078789814 doi "https://doi.org/10.1016/s0378-8741(03)00072-2" @default.
• W2078789814 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12738096" @default.
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