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- W2078804895 abstract "IMAGE FORMATION IN OPTICAL COHERENCE ELASTOGRAPHY (OCE) RESULTS FROM A COMBINATION OF TWO PROCESSES: the mechanical deformation imparted to the sample and the detection of the resulting displacement using optical coherence tomography (OCT). We present a multiphysics model of these processes, validated by simulating strain elastograms acquired using phase-sensitive compression OCE, and demonstrating close correspondence with experimental results. Using the model, we present evidence that the approximation commonly used to infer sample displacement in phase-sensitive OCE is invalidated for smaller deformations than has been previously considered, significantly affecting the measurement precision, as quantified by the displacement sensitivity and the elastogram signal-to-noise ratio. We show how the precision of OCE is affected not only by OCT shot-noise, as is usually considered, but additionally by phase decorrelation due to the sample deformation. This multiphysics model provides a general framework that could be used to compare and contrast different OCE techniques." @default.
- W2078804895 created "2016-06-24" @default.
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- W2078804895 date "2014-08-01" @default.
- W2078804895 modified "2023-10-01" @default.
- W2078804895 title "Analysis of image formation in optical coherence elastography using a multiphysics approach" @default.
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- W2078804895 doi "https://doi.org/10.1364/boe.5.002913" @default.
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