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- W2078805384 abstract "To evaluate the effects of a single dose of trazodone on the standardized field sobriety test (SFST).A randomized, double-blinded, repeated-measures study.Forty-five healthy adult subjects.University campus.The SFST consists of the horizontal gaze nystagmus, walk-and-turn, and one-leg stand tests. Subjects were administered a baseline SFST and at 2 hours after the administration of either trazodone 100 mg (30 subjects) or acetaminophen 650 mg (15 subjects). At 2 hours post drug administration, there were no statistical differences in failure rates between the trazodone and acetaminophen groups (53.3% vs 20.0%, p=0.054). However, the trazodone group exhibited more impairment clues within the individual tests of the SFST than the acetaminophen group.A one-time dose of trazodone 100 mg does not result in an increased SFST failure rate at 2 hours postdosing compared to acetaminophen 650 mg. However, the number of individual impairment clues detected is increased with trazodone. Trazodone 100 mg may cause cognitive driving impairment." @default.
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- W2078805384 date "2013-02-28" @default.
- W2078805384 modified "2023-09-27" @default.
- W2078805384 title "The Effect of Trazodone on Standardized Field Sobriety Tests" @default.
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- W2078805384 doi "https://doi.org/10.1002/phar.1210" @default.
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