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- W2078839096 abstract "Background An exaggerated decrease in diastolic blood pressure (DBP) upon raising the upper extremity is a sign of severe chronic aortic regurgitation (AR) (Mayne's sign). However, this finding was proposed prior to the widespread use of Doppler echocardiography. Objective To determine the relation between Doppler echo determined AR and changes in DBP. Methods We prospectively studied 30 controls without AR and 40 patients (69±15 years) with AR ranging from mild to severe and measured DBP before and during upper extremity raising. Results The change in DBP was inversely correlated with age (r=−0.41, P<0.001) but not to the presence or severity of AR on Doppler echocardiography (r=−0.10, P=0.42). Conclusion Greater decreases in DBP upon arm raising appear to be related to younger age but not to the presence or severity of AR. Therefore, Mayne's sign should not be considered a reliable finding of regurgitant aortic valve flow." @default.
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- W2078839096 date "2010-12-01" @default.
- W2078839096 modified "2023-10-18" @default.
- W2078839096 title "Mayne's sign is mainly related to younger age and not to aortic regurgitation" @default.
- W2078839096 doi "https://doi.org/10.1097/mbp.0b013e328340ff3b" @default.
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