FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078855247> ?p ?o ?g. }

• W2078855247 endingPage "366" @default.
• W2078855247 startingPage "359" @default.
• W2078855247 abstract "It has been revealed that skeletal muscle cells have the potential to generate, sense and respond to biomechanical signals and that, mechanical force is one of the important factors influencing proliferation, differentiation, regeneration and homeostasis of skeletal muscle cells and myoblasts. The aim of this study was to illustrate the effect of cyclic uniaxial strain on myogenic differentiation of adipose-derived stem cells (ASCs). This study was designed to investigate this effect within 3 days in 4 groups: control (untreated), chemical, chemical-mechanical and mechanical based on exposure of ASCs to chemical growth factors for 3 days or to mechanical strain just on the 2nd day. Finally, cell orientation, muscle-related gene expression, myosin protein synthesis and the number of myosin-positive cells were examined to estimate the rate of differentiation. By studying the cells before and after exposure to uniaxial strain, it could be observed that by exerting the load, the cells were organized almost perpendicularly to strain direction. Real-time RT-PCR demonstrated that uniaxial strain had a significant effect on up-regulation of muscle-related genes in chemical–mechanical group (P < 0.001) as compared to mechanical or chemical groups. Immunocytochemistry confirmed the myosin-positive cells in treated groups and the numbers of these cells were enumerated by flow cytometry. These data suggest that uniaxial cyclic strain could affect ASCs and cause their myogenic differentiation and that the combination of chemical myogenic differentiation factors with mechanical signals promotes differentiation much more than differentiation by chemical myogenic differentiation factors or mechanical signals alone." @default.
• W2078855247 created "2016-06-24" @default.
• W2078855247 creator A5004772897 @default.
• W2078855247 creator A5041517066 @default.
• W2078855247 creator A5055177713 @default.
• W2078855247 creator A5071896350 @default.
• W2078855247 creator A5074645389 @default.
• W2078855247 creator A5075528646 @default.
• W2078855247 creator A5088377096 @default.
• W2078855247 date "2011-12-01" @default.
• W2078855247 modified "2023-10-18" @default.
• W2078855247 title "The evaluation of cyclic uniaxial strain on myogenic differentiation of adipose-derived stem cells" @default.
• W2078855247 cites W1964693426 @default.
• W2078855247 cites W1969004153 @default.
• W2078855247 cites W1969655939 @default.
• W2078855247 cites W1985015512 @default.
• W2078855247 cites W1991761391 @default.
• W2078855247 cites W1994923567 @default.
• W2078855247 cites W1998646921 @default.
• W2078855247 cites W2002045126 @default.
• W2078855247 cites W2002575281 @default.
• W2078855247 cites W2006437698 @default.
• W2078855247 cites W2009144332 @default.
• W2078855247 cites W2016673036 @default.
• W2078855247 cites W2025442971 @default.
• W2078855247 cites W2030436637 @default.
• W2078855247 cites W2032689019 @default.
• W2078855247 cites W2037588873 @default.
• W2078855247 cites W2048436626 @default.
• W2078855247 cites W2049367841 @default.
• W2078855247 cites W2065460430 @default.
• W2078855247 cites W2074290309 @default.
• W2078855247 cites W2080472732 @default.
• W2078855247 cites W2081544530 @default.
• W2078855247 cites W2081791895 @default.
• W2078855247 cites W2082419440 @default.
• W2078855247 cites W2084397891 @default.
• W2078855247 cites W2087229871 @default.
• W2078855247 cites W2115062578 @default.
• W2078855247 cites W2116572430 @default.
• W2078855247 cites W2126684538 @default.
• W2078855247 cites W2130248622 @default.
• W2078855247 cites W2144265390 @default.
• W2078855247 cites W2147742177 @default.
• W2078855247 cites W2158506340 @default.
• W2078855247 cites W2169906660 @default.
• W2078855247 cites W2171405699 @default.
• W2078855247 doi "https://doi.org/10.1016/j.tice.2011.07.004" @default.
• W2078855247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21872289" @default.
• W2078855247 hasPublicationYear "2011" @default.
• W2078855247 type Work @default.
• W2078855247 sameAs 2078855247 @default.
• W2078855247 citedByCount "41" @default.
• W2078855247 countsByYear W20788552472012 @default.
• W2078855247 countsByYear W20788552472013 @default.
• W2078855247 countsByYear W20788552472014 @default.
• W2078855247 countsByYear W20788552472015 @default.
• W2078855247 countsByYear W20788552472016 @default.
• W2078855247 countsByYear W20788552472017 @default.
• W2078855247 countsByYear W20788552472018 @default.
• W2078855247 countsByYear W20788552472019 @default.
• W2078855247 countsByYear W20788552472020 @default.
• W2078855247 countsByYear W20788552472021 @default.
• W2078855247 crossrefType "journal-article" @default.
• W2078855247 hasAuthorship W2078855247A5004772897 @default.
• W2078855247 hasAuthorship W2078855247A5041517066 @default.
• W2078855247 hasAuthorship W2078855247A5055177713 @default.
• W2078855247 hasAuthorship W2078855247A5071896350 @default.
• W2078855247 hasAuthorship W2078855247A5074645389 @default.
• W2078855247 hasAuthorship W2078855247A5075528646 @default.
• W2078855247 hasAuthorship W2078855247A5088377096 @default.
• W2078855247 hasConcept C104317684 @default.
• W2078855247 hasConcept C105702510 @default.
• W2078855247 hasConcept C134018914 @default.
• W2078855247 hasConcept C148738053 @default.
• W2078855247 hasConcept C159985019 @default.
• W2078855247 hasConcept C171089720 @default.
• W2078855247 hasConcept C192562407 @default.
• W2078855247 hasConcept C207200792 @default.
• W2078855247 hasConcept C2778022156 @default.
• W2078855247 hasConcept C2778383842 @default.
• W2078855247 hasConcept C2779959927 @default.
• W2078855247 hasConcept C28328180 @default.
• W2078855247 hasConcept C35866371 @default.
• W2078855247 hasConcept C55493867 @default.
• W2078855247 hasConcept C6997183 @default.
• W2078855247 hasConcept C86803240 @default.
• W2078855247 hasConcept C95444343 @default.
• W2078855247 hasConceptScore W2078855247C104317684 @default.
• W2078855247 hasConceptScore W2078855247C105702510 @default.
• W2078855247 hasConceptScore W2078855247C134018914 @default.
• W2078855247 hasConceptScore W2078855247C148738053 @default.
• W2078855247 hasConceptScore W2078855247C159985019 @default.
• W2078855247 hasConceptScore W2078855247C171089720 @default.
• W2078855247 hasConceptScore W2078855247C192562407 @default.
• W2078855247 hasConceptScore W2078855247C207200792 @default.
• W2078855247 hasConceptScore W2078855247C2778022156 @default.
• W2078855247 hasConceptScore W2078855247C2778383842 @default.

• next