Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078857874> ?p ?o ?g. }
- W2078857874 endingPage "38" @default.
- W2078857874 startingPage "27" @default.
- W2078857874 abstract "A method for reflectance in situ hybridization (RISH) is presented. The importance of the method is demonstrated by results obtained on cytological and histological breast cancer specimens. Scattering reflectance signals from 1-nm colloidal-gold particles after RNA/RNA in situ hybridization, using digoxigenin-labelled riboprobes, were detected by confocal scanning laser microscopy. The mRNA expression of two ras-related genes, rho B and rho C, was analysed in human histological breast cancer specimens and in human breast cancer cell lines. Horizontal (x, y) and vertical (z) optical sections after three-dimensional imaging were used for visualization. A marked heterogeneity (between individual cells and between specimens) was noted for the expression of the rho B gene, both in cytological and in histological samples. On the other hand, rho C was always expressed and showed no heterogeneity. This method allows the identification of several cellular constituents in an heterogeneous tissue structure, as demonstrated by the simultaneous detection of rho B (or rho C) by reflectance and of DNA, cytokeratin and/or vimentin by fluorescence." @default.
- W2078857874 created "2016-06-24" @default.
- W2078857874 creator A5003752789 @default.
- W2078857874 creator A5004905312 @default.
- W2078857874 creator A5012603842 @default.
- W2078857874 creator A5024590935 @default.
- W2078857874 creator A5035265554 @default.
- W2078857874 creator A5038767437 @default.
- W2078857874 creator A5060148724 @default.
- W2078857874 date "1994-01-01" @default.
- W2078857874 modified "2023-10-01" @default.
- W2078857874 title "Reflectance in situ hybridization (RISH): detection, by confocal reflectance laser microscopy, of gold-labelled riboprobes in breast cancer cell lines and histological specimens" @default.
- W2078857874 cites W1246406349 @default.
- W2078857874 cites W1972697724 @default.
- W2078857874 cites W1973319827 @default.
- W2078857874 cites W1999074985 @default.
- W2078857874 cites W2001519402 @default.
- W2078857874 cites W2007660746 @default.
- W2078857874 cites W2009993853 @default.
- W2078857874 cites W2011382883 @default.
- W2078857874 cites W2014038908 @default.
- W2078857874 cites W2017507322 @default.
- W2078857874 cites W2017685202 @default.
- W2078857874 cites W2017797632 @default.
- W2078857874 cites W2017949119 @default.
- W2078857874 cites W2019960738 @default.
- W2078857874 cites W2033988932 @default.
- W2078857874 cites W2039529706 @default.
- W2078857874 cites W2040593543 @default.
- W2078857874 cites W2042088496 @default.
- W2078857874 cites W2042562742 @default.
- W2078857874 cites W2043625046 @default.
- W2078857874 cites W2046955948 @default.
- W2078857874 cites W2051819610 @default.
- W2078857874 cites W2052567292 @default.
- W2078857874 cites W2062188111 @default.
- W2078857874 cites W2068417948 @default.
- W2078857874 cites W2073006936 @default.
- W2078857874 cites W2073131935 @default.
- W2078857874 cites W2076869028 @default.
- W2078857874 cites W2077763704 @default.
- W2078857874 cites W2078523265 @default.
- W2078857874 cites W2082632351 @default.
- W2078857874 cites W2093060774 @default.
- W2078857874 cites W2103885797 @default.
- W2078857874 cites W2121578988 @default.
- W2078857874 cites W2139936305 @default.
- W2078857874 cites W2162923437 @default.
- W2078857874 cites W2480082357 @default.
- W2078857874 doi "https://doi.org/10.1111/j.1365-2818.1994.tb03425.x" @default.
- W2078857874 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7509879" @default.
- W2078857874 hasPublicationYear "1994" @default.
- W2078857874 type Work @default.
- W2078857874 sameAs 2078857874 @default.
- W2078857874 citedByCount "24" @default.
- W2078857874 crossrefType "journal-article" @default.
- W2078857874 hasAuthorship W2078857874A5003752789 @default.
- W2078857874 hasAuthorship W2078857874A5004905312 @default.
- W2078857874 hasAuthorship W2078857874A5012603842 @default.
- W2078857874 hasAuthorship W2078857874A5024590935 @default.
- W2078857874 hasAuthorship W2078857874A5035265554 @default.
- W2078857874 hasAuthorship W2078857874A5038767437 @default.
- W2078857874 hasAuthorship W2078857874A5060148724 @default.
- W2078857874 hasConcept C104317684 @default.
- W2078857874 hasConcept C120665830 @default.
- W2078857874 hasConcept C121332964 @default.
- W2078857874 hasConcept C136009344 @default.
- W2078857874 hasConcept C142724271 @default.
- W2078857874 hasConcept C147080431 @default.
- W2078857874 hasConcept C147447768 @default.
- W2078857874 hasConcept C150194340 @default.
- W2078857874 hasConcept C153911025 @default.
- W2078857874 hasConcept C178790620 @default.
- W2078857874 hasConcept C185592680 @default.
- W2078857874 hasConcept C192562407 @default.
- W2078857874 hasConcept C204232928 @default.
- W2078857874 hasConcept C2776552150 @default.
- W2078857874 hasConcept C2777542201 @default.
- W2078857874 hasConcept C2777822432 @default.
- W2078857874 hasConcept C2779012181 @default.
- W2078857874 hasConcept C2779178360 @default.
- W2078857874 hasConcept C30481170 @default.
- W2078857874 hasConcept C55493867 @default.
- W2078857874 hasConcept C71924100 @default.
- W2078857874 hasConcept C81439078 @default.
- W2078857874 hasConcept C86803240 @default.
- W2078857874 hasConcept C95444343 @default.
- W2078857874 hasConceptScore W2078857874C104317684 @default.
- W2078857874 hasConceptScore W2078857874C120665830 @default.
- W2078857874 hasConceptScore W2078857874C121332964 @default.
- W2078857874 hasConceptScore W2078857874C136009344 @default.
- W2078857874 hasConceptScore W2078857874C142724271 @default.
- W2078857874 hasConceptScore W2078857874C147080431 @default.
- W2078857874 hasConceptScore W2078857874C147447768 @default.
- W2078857874 hasConceptScore W2078857874C150194340 @default.
- W2078857874 hasConceptScore W2078857874C153911025 @default.
- W2078857874 hasConceptScore W2078857874C178790620 @default.
- W2078857874 hasConceptScore W2078857874C185592680 @default.