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• W2078864291 abstract "The objective of the study was to evaluate whether typing of human papillomavirus (HPV) among women with low-grade cervical cytology can improve the ability to identify women with cervical cancer or cervical intraepithelial neoplasia grade III (CIN III or worse).A total of 1595 women with low-grade cervical cytology participating in a randomized implementation trial of HPV triaging using Hybrid Capture II were also HPV genotyped and CIN III or worse predictive values evaluated.HPV 16 was detected in 57% of cases with CIN III or worse but only among 24% of all tested women. Testing for the 3 HPV types with highest risk (HPV16/31/33) detected 77% of CIN III or worse, with 36% of women testing positive. Positivity for the other high-risk HPV types had a decreased risk for CIN III or worse.Different high-risk HPV types confer different risks for the presence of CIN III or worse, implying that HPV genotyping could be useful for the optimization of triaging strategies." @default.
• W2078864291 created "2016-06-24" @default.
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• W2078864291 date "2011-08-01" @default.
• W2078864291 modified "2023-10-03" @default.
• W2078864291 title "Genotyping of human papillomavirus in triaging of low-grade cervical cytology" @default.
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• W2078864291 doi "https://doi.org/10.1016/j.ajog.2011.03.056" @default.
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