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- W2078873107 abstract "The research of estrogen receptor (ER) ligands has benefited in the last decade from the implementation of combinatorial chemistry. The general pharmacophore has been identified and subsequently a multitude of compounds have been synthesized. Surprisingly, up to now simple amides have not been taken into consideration. Here we show that amides resulting from the condensation of hydroxybenzoic acids with aminophenols result in compounds retaining the pharmacophore structure of an ER ligand with a clear estrogenic activity." @default.
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- W2078873107 date "2011-12-14" @default.
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- W2078873107 title "<i>N</i>-Arylbenzamides: extremely simple scaffolds for the development of novel estrogen receptor agonists" @default.
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- W2078873107 doi "https://doi.org/10.3109/14756366.2011.642374" @default.
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