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- W2078896295 abstract "At least three types of mRNA of the catalytic subunit of Na,K-ATPase namely α-,α+- and α3-isoforms are identified in different tissues. Only two of them α and α+ have well known structural and catalytic properties. Here we present immunochemical data indicating that the α3 protein really exists in pig and human kidney, and human brain. Crude membrane fractions and purified membrane-bound Na,K-ATPases were immunoblotted with α3-specific antibodies raised against the synthetic peptide corresponding to the unique sequence of this isoform. The mature α3-subunit is shown to include the sequence GDKKDDKSSPK followed by the initiating methionine residue. Nephron collecting tubules are proposed to specifically contain Na,K-ATPase α3-isoform." @default.
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- W2078896295 date "1989-07-03" @default.
- W2078896295 modified "2023-09-25" @default.
- W2078896295 title "Immunodetection of Na,K-ATPase α3-isoform in renal and nerve tissues" @default.
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- W2078896295 doi "https://doi.org/10.1016/0014-5793(89)80793-8" @default.
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