Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078904969> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2078904969 endingPage "255" @default.
- W2078904969 startingPage "247" @default.
- W2078904969 abstract "The effects of phenformin on glucose and water absorption from isolated perfused rat small intestine were studied. Luminal phenformin inhibited glucose and water absorption progressively as its concentration was increased from 0·1–1·0 mg.ml-1. At 0·5 mg phenformin ml-1, inhibition increased with time of exposure to phenformin up to 15 min and thereafter remained constant. Arterial infusion of phenformin (1·0 mg.ml-1) produced less inhibition of glucose and water absorption. The site of phenformin's action appeared to be intracellular. Phenformin absorption from a luminal perfusate (0·5 mg.ml−1) was measured. Although it was rapidly absorbed (224 µg.cm intestine−1.h−1) from the lumen, less than 2 µg.cm−1.h−1 appeared at the serosal surface of the intestine. In subsequent phenformin-free perfusion, only 25% of the absorbed phenformin was recovered in the luminal and serosal effluents." @default.
- W2078904969 created "2016-06-24" @default.
- W2078904969 creator A5025867205 @default.
- W2078904969 creator A5057105491 @default.
- W2078904969 date "1977-07-16" @default.
- W2078904969 modified "2023-10-10" @default.
- W2078904969 title "THE ABSORPTION OF PHENFORMIN AND ITS EFFECTS ON GLUCOSE AND WATER ABSORPTION IN ISOLATED PERFUSED RAT SMALL INTESTINE" @default.
- W2078904969 doi "https://doi.org/10.1113/expphysiol.1977.sp002396" @default.
- W2078904969 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/588021" @default.
- W2078904969 hasPublicationYear "1977" @default.
- W2078904969 type Work @default.
- W2078904969 sameAs 2078904969 @default.
- W2078904969 citedByCount "3" @default.
- W2078904969 countsByYear W20789049692017 @default.
- W2078904969 crossrefType "journal-article" @default.
- W2078904969 hasAuthorship W2078904969A5025867205 @default.
- W2078904969 hasAuthorship W2078904969A5057105491 @default.
- W2078904969 hasBestOaLocation W20789049691 @default.
- W2078904969 hasConcept C125287762 @default.
- W2078904969 hasConcept C126322002 @default.
- W2078904969 hasConcept C131631996 @default.
- W2078904969 hasConcept C134018914 @default.
- W2078904969 hasConcept C159985019 @default.
- W2078904969 hasConcept C185592680 @default.
- W2078904969 hasConcept C192562407 @default.
- W2078904969 hasConcept C2777882243 @default.
- W2078904969 hasConcept C2778877718 @default.
- W2078904969 hasConcept C2779306644 @default.
- W2078904969 hasConcept C2780323712 @default.
- W2078904969 hasConcept C55493867 @default.
- W2078904969 hasConcept C71924100 @default.
- W2078904969 hasConcept C79879829 @default.
- W2078904969 hasConceptScore W2078904969C125287762 @default.
- W2078904969 hasConceptScore W2078904969C126322002 @default.
- W2078904969 hasConceptScore W2078904969C131631996 @default.
- W2078904969 hasConceptScore W2078904969C134018914 @default.
- W2078904969 hasConceptScore W2078904969C159985019 @default.
- W2078904969 hasConceptScore W2078904969C185592680 @default.
- W2078904969 hasConceptScore W2078904969C192562407 @default.
- W2078904969 hasConceptScore W2078904969C2777882243 @default.
- W2078904969 hasConceptScore W2078904969C2778877718 @default.
- W2078904969 hasConceptScore W2078904969C2779306644 @default.
- W2078904969 hasConceptScore W2078904969C2780323712 @default.
- W2078904969 hasConceptScore W2078904969C55493867 @default.
- W2078904969 hasConceptScore W2078904969C71924100 @default.
- W2078904969 hasConceptScore W2078904969C79879829 @default.
- W2078904969 hasIssue "3" @default.
- W2078904969 hasLocation W20789049691 @default.
- W2078904969 hasLocation W20789049692 @default.
- W2078904969 hasOpenAccess W2078904969 @default.
- W2078904969 hasPrimaryLocation W20789049691 @default.
- W2078904969 hasRelatedWork W1918412247 @default.
- W2078904969 hasRelatedWork W1965328949 @default.
- W2078904969 hasRelatedWork W2017440363 @default.
- W2078904969 hasRelatedWork W2021622121 @default.
- W2078904969 hasRelatedWork W2067721066 @default.
- W2078904969 hasRelatedWork W2086252815 @default.
- W2078904969 hasRelatedWork W2095423290 @default.
- W2078904969 hasRelatedWork W2130667046 @default.
- W2078904969 hasRelatedWork W2304027217 @default.
- W2078904969 hasRelatedWork W2417190956 @default.
- W2078904969 hasVolume "62" @default.
- W2078904969 isParatext "false" @default.
- W2078904969 isRetracted "false" @default.
- W2078904969 magId "2078904969" @default.
- W2078904969 workType "article" @default.