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- W2078904975 abstract "MUM1/IRF4 protein is a member of the interferon regulatory factor (IRF) family of transcriptional factors initially described as downstream regulators of interferon signaling. The quantity of this factor varies within the hematopoietic system in a lineage and stage-specific way. It is considered to be a key regulator of several steps in lymphoid, myeloid, and dendritic cell differentiation and maturation. MUM1/IRF4 expression is observed in many lymphoid and myeloid malignancies, and may be a promising target for the treatment of some of these neoplasms. We reviewed the literature on MUM1/IRF4, with emphasis on the pathologic aspects of this marker in reactive and malignant hematologic and nonhematologic conditions." @default.
- W2078904975 created "2016-06-24" @default.
- W2078904975 creator A5023734653 @default.
- W2078904975 creator A5038989449 @default.
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- W2078904975 date "2010-07-01" @default.
- W2078904975 modified "2023-10-16" @default.
- W2078904975 title "MUM1/IRF4" @default.
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- W2078904975 doi "https://doi.org/10.1097/pai.0b013e3181cf1126" @default.
- W2078904975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20182347" @default.
- W2078904975 hasPublicationYear "2010" @default.
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