Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078962621> ?p ?o ?g. }
- W2078962621 endingPage "3796" @default.
- W2078962621 startingPage "3785" @default.
- W2078962621 abstract "Recently we characterised a novel 29 kDa endoplasmic reticulum protein that is widely expressed in rat tissues, and named it ERp29. Several ERp29-like gene products have been reported in human tissues but uncertainty surrounds their relationships with each other and rat ERp29. To clarify these issues, ERp29 was isolated from human liver and characterised by primary structural analysis and two-dimensional gel mapping. Comparisons with rat ERp29 revealed striking homologies both in sequence and physical properties. Characterisation of the isoelectric heterogeneity and anomalous mass on two-dimensional gels enabled two reported homologues (UL35 and ERp31) to be identified as ERp29. Resolution of a sequence discrepancy led to unequivocal correlation of human ERp29 with the cognate cDNA previously named ERp31 and ERp28. Consequent links established to human genome and proteome projects showed that ERp29 is encoded by a gene on chromosome 12 that is expressed universally in human tissues. Together, these findings unified various ERp29 homologues as products of a single gene orthologous to rat ERp29 and established ERp29 as the only known member of a new protein class. Investigations of ERp29 function in human health and disease should benefit from the integrated links between genome, proteome and murine model organisms established here.*" @default.
- W2078962621 created "2016-06-24" @default.
- W2078962621 creator A5043034568 @default.
- W2078962621 creator A5045443255 @default.
- W2078962621 date "2000-11-01" @default.
- W2078962621 modified "2023-09-29" @default.
- W2078962621 title "Human ERp29: Isolation, primary structural characterisation and two-dimensional gel mapping" @default.
- W2078962621 cites W1487568705 @default.
- W2078962621 cites W1514223875 @default.
- W2078962621 cites W1605843386 @default.
- W2078962621 cites W164222030 @default.
- W2078962621 cites W164666323 @default.
- W2078962621 cites W1653713408 @default.
- W2078962621 cites W1919835673 @default.
- W2078962621 cites W1951130234 @default.
- W2078962621 cites W1965144118 @default.
- W2078962621 cites W1967099091 @default.
- W2078962621 cites W1973203775 @default.
- W2078962621 cites W1975085160 @default.
- W2078962621 cites W1988587727 @default.
- W2078962621 cites W1990453950 @default.
- W2078962621 cites W1995571726 @default.
- W2078962621 cites W2001200460 @default.
- W2078962621 cites W2003258557 @default.
- W2078962621 cites W2004357092 @default.
- W2078962621 cites W2005673211 @default.
- W2078962621 cites W2011227302 @default.
- W2078962621 cites W2014724361 @default.
- W2078962621 cites W2019619637 @default.
- W2078962621 cites W2025391005 @default.
- W2078962621 cites W2031296028 @default.
- W2078962621 cites W2036503551 @default.
- W2078962621 cites W2036778801 @default.
- W2078962621 cites W2051793369 @default.
- W2078962621 cites W2055592745 @default.
- W2078962621 cites W2058202183 @default.
- W2078962621 cites W2063249853 @default.
- W2078962621 cites W2064323228 @default.
- W2078962621 cites W2075445100 @default.
- W2078962621 cites W2091723153 @default.
- W2078962621 cites W2092999292 @default.
- W2078962621 cites W2101971141 @default.
- W2078962621 cites W2107339893 @default.
- W2078962621 cites W2108209352 @default.
- W2078962621 cites W2109722929 @default.
- W2078962621 cites W2121418514 @default.
- W2078962621 cites W2169898794 @default.
- W2078962621 cites W2171882089 @default.
- W2078962621 cites W4235927881 @default.
- W2078962621 doi "https://doi.org/10.1002/1522-2683(200011)21:17<3785::aid-elps3785>3.0.co;2-2" @default.
- W2078962621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11271497" @default.
- W2078962621 hasPublicationYear "2000" @default.
- W2078962621 type Work @default.
- W2078962621 sameAs 2078962621 @default.
- W2078962621 citedByCount "31" @default.
- W2078962621 countsByYear W20789626212014 @default.
- W2078962621 countsByYear W20789626212015 @default.
- W2078962621 countsByYear W20789626212016 @default.
- W2078962621 countsByYear W20789626212021 @default.
- W2078962621 crossrefType "journal-article" @default.
- W2078962621 hasAuthorship W2078962621A5043034568 @default.
- W2078962621 hasAuthorship W2078962621A5045443255 @default.
- W2078962621 hasConcept C104317684 @default.
- W2078962621 hasConcept C104397665 @default.
- W2078962621 hasConcept C141231307 @default.
- W2078962621 hasConcept C158617107 @default.
- W2078962621 hasConcept C187882448 @default.
- W2078962621 hasConcept C197077220 @default.
- W2078962621 hasConcept C54355233 @default.
- W2078962621 hasConcept C70721500 @default.
- W2078962621 hasConcept C86803240 @default.
- W2078962621 hasConceptScore W2078962621C104317684 @default.
- W2078962621 hasConceptScore W2078962621C104397665 @default.
- W2078962621 hasConceptScore W2078962621C141231307 @default.
- W2078962621 hasConceptScore W2078962621C158617107 @default.
- W2078962621 hasConceptScore W2078962621C187882448 @default.
- W2078962621 hasConceptScore W2078962621C197077220 @default.
- W2078962621 hasConceptScore W2078962621C54355233 @default.
- W2078962621 hasConceptScore W2078962621C70721500 @default.
- W2078962621 hasConceptScore W2078962621C86803240 @default.
- W2078962621 hasIssue "17" @default.
- W2078962621 hasLocation W20789626211 @default.
- W2078962621 hasLocation W20789626212 @default.
- W2078962621 hasOpenAccess W2078962621 @default.
- W2078962621 hasPrimaryLocation W20789626211 @default.
- W2078962621 hasRelatedWork W1603543036 @default.
- W2078962621 hasRelatedWork W1946031417 @default.
- W2078962621 hasRelatedWork W1994927702 @default.
- W2078962621 hasRelatedWork W2069184423 @default.
- W2078962621 hasRelatedWork W2109946226 @default.
- W2078962621 hasRelatedWork W2238553258 @default.
- W2078962621 hasRelatedWork W2549117626 @default.
- W2078962621 hasRelatedWork W2903984190 @default.
- W2078962621 hasRelatedWork W4377098514 @default.
- W2078962621 hasRelatedWork W2187207551 @default.
- W2078962621 hasVolume "21" @default.
- W2078962621 isParatext "false" @default.
- W2078962621 isRetracted "false" @default.