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- W2078971810 abstract "ISEE-0796 Background and Objective: Epidemiologists at the U.S. National Cancer Institute (NCI) conducted two large scale studies that include location of residential histories over participant lifetimes. We discuss the degree of mobility of these participants and its impact on conducting exposure assessment of environmental contaminants. Methods: We received addresses from 2,611 participants in a New England Health and Environment Study (NEHES) concerning arsenic and disinfection byproducts (DBP) in water supply, and from 2,378 in a SEER-NHL Study (NCINHL) concerning proximity to dioxin-emitting facilities. We geocoded locations for both studies using address-matching software followed up by interactive manual geocoding of inexact matches. We used a GIS to analyze the degree of mobility in each study population and its impact on exposure metrics used in each epidemiological study. Results: We found 69% of the study population in NEHES (55% in NCINHL) moved at least 7 times over an average residential history of 69 and 57 years, respectively. The average number of residences per participant was 10 and 7. In NEHES residential relocations for 88% of participants resulted in a change in water supply source, an important variable in estimating arsenic and DBP exposure. In NCINHL 366 participants resided within 2 km of a dioxin-emitting facility between 1987 and their reference year (1998–2000). 25% of these participants had more than one residence during this exposure period, resulting in a change in proximity to type, distance, and/or number of dioxin emitting facilities. Conclusions: Results from the analysis of residential mobility in two large scale cancer epidemiological studies of environmental contaminants indicate it could have significant impact on exposure assessment in terms of changes in contaminant source at different residence locations. The degree of impact will be a function of the change in concentration of the contaminant due to relocation." @default.
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- W2078971810 date "2009-11-01" @default.
- W2078971810 modified "2023-09-26" @default.
- W2078971810 title "The Impact of Residential Mobility on Exposure Assessment in Cancer Epidemiology" @default.
- W2078971810 doi "https://doi.org/10.1097/01.ede.0000362867.79502.20" @default.
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