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- W2078987964 abstract "A capsule formulation containing 50 mg of isosorbide mononitrate has been developed, 30% of which is in a nonsustained-release form to ensure rapid attainment of initial plasma levels. The remaining 70% is in a sustained-release form that ensures a long-lasting effect and the convenience of once-daily dosing. This formulation of sustained-release isosorbide mononitrate (Elantan LA 50 mg) provides plasma levels greater than 100 ng/ml for 17 hours after oral administration. For the remaining 7 hours, the nitrate plasma level ranges between 50 and 100 ng/ml." @default.
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- W2078987964 date "1988-03-01" @default.
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- W2078987964 title "Sustained-release isosorbide mononitrate (50 mg): Optimization of a once-daily dosage form for long-term treatment of angina pectoris" @default.
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- W2078987964 doi "https://doi.org/10.1016/0002-9149(88)90082-3" @default.
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