FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2078990818> ?p ?o ?g. }

• W2078990818 endingPage "321" @default.
• W2078990818 startingPage "315" @default.
• W2078990818 abstract "Pemphigus vulgaris (PV) is a potentially fatal blistering disease of the skin and mucous membranes, characterized by the presence of autoantibodies against adhesion molecules (desmoglein, Dsg3) present on the surface of keratinocytes, which lead to the loss of cellular adhesion or acantholysis. The mainstay of treatment is conventional immunosuppressive therapy (CIST), i.e. high dose, long-term systemic corticosteroids with or without immunosuppressive drugs. Intravenous immunoglobulin (IVIg) has been used in patients refractory to CIST, and its use has resulted in long-term clinical remission. Since cytokines play an important role in the immunopathogenesis of PV, it would be useful to compare how both IVIg and CIST therapies affect cytokine levels in the serum of PV patients. Thus, the goal of this study was to conduct a comparative analysis of levels of various cytokines, during an 18 month consecutive period, after the initiation of CIST or IVIg treatment in PV patients, with similar extent and severity of disease in the two study groups, with 11 patients in each group. The cytokines measured were IL-1β, IL-6, IL-8, IFN-γ, IL-4 and IL-10. The levels of most of these cytokines were higher in the sera of untreated patients in both groups, compared to normal controls. The cumulative data collected over an 18 month period of treatment demonstrates that there is a gradual reduction in the levels of these cytokines, until they are at levels observed in normal individuals. The conclusions from this limited number of patients, prospectively studied, would suggest that both CIST and IVIg therapies are similar in their ability to influence a panel of cytokines in patients with pemphigus vulgaris." @default.
• W2078990818 created "2016-06-24" @default.
• W2078990818 creator A5000801624 @default.
• W2078990818 creator A5025546339 @default.
• W2078990818 creator A5046066980 @default.
• W2078990818 creator A5061811305 @default.
• W2078990818 date "2008-03-01" @default.
• W2078990818 modified "2023-10-16" @default.
• W2078990818 title "Cytokine profiles in pemphigus vulgaris patients treated with intravenous immunoglobulins as compared to conventional immunosuppressive therapy" @default.
• W2078990818 cites W157857262 @default.
• W2078990818 cites W188853335 @default.
• W2078990818 cites W1976535033 @default.
• W2078990818 cites W1976537150 @default.
• W2078990818 cites W1977282646 @default.
• W2078990818 cites W1988264627 @default.
• W2078990818 cites W1992817657 @default.
• W2078990818 cites W1993267543 @default.
• W2078990818 cites W2000792258 @default.
• W2078990818 cites W2001435680 @default.
• W2078990818 cites W2010287671 @default.
• W2078990818 cites W2011312402 @default.
• W2078990818 cites W2015479114 @default.
• W2078990818 cites W2017996215 @default.
• W2078990818 cites W2024136187 @default.
• W2078990818 cites W2026307959 @default.
• W2078990818 cites W2027916433 @default.
• W2078990818 cites W2031680195 @default.
• W2078990818 cites W2032636193 @default.
• W2078990818 cites W2033822124 @default.
• W2078990818 cites W2038624692 @default.
• W2078990818 cites W2039072312 @default.
• W2078990818 cites W2040580298 @default.
• W2078990818 cites W2043106635 @default.
• W2078990818 cites W2051070057 @default.
• W2078990818 cites W2053257655 @default.
• W2078990818 cites W2053684390 @default.
• W2078990818 cites W2053730359 @default.
• W2078990818 cites W2058850702 @default.
• W2078990818 cites W2066551696 @default.
• W2078990818 cites W2073512163 @default.
• W2078990818 cites W2074940561 @default.
• W2078990818 cites W2078295357 @default.
• W2078990818 cites W2078439504 @default.
• W2078990818 cites W2084589613 @default.
• W2078990818 cites W2084805051 @default.
• W2078990818 cites W2100523555 @default.
• W2078990818 cites W2109460539 @default.
• W2078990818 cites W2110334588 @default.
• W2078990818 cites W2116001615 @default.
• W2078990818 cites W2125076165 @default.
• W2078990818 cites W2125280361 @default.
• W2078990818 cites W2134851 @default.
• W2078990818 cites W2137658161 @default.
• W2078990818 cites W2144233065 @default.
• W2078990818 cites W2144302344 @default.
• W2078990818 cites W2145359582 @default.
• W2078990818 cites W2151305184 @default.
• W2078990818 cites W2151338546 @default.
• W2078990818 cites W2160343444 @default.
• W2078990818 cites W2161738616 @default.
• W2078990818 cites W2162864505 @default.
• W2078990818 cites W2317276018 @default.
• W2078990818 cites W2319620963 @default.
• W2078990818 cites W2374161697 @default.
• W2078990818 cites W2616639792 @default.
• W2078990818 cites W3116890861 @default.
• W2078990818 cites W4211091472 @default.
• W2078990818 cites W4211222501 @default.
• W2078990818 cites W4234827406 @default.
• W2078990818 cites W4243967529 @default.
• W2078990818 cites W4254636038 @default.
• W2078990818 cites W4255278269 @default.
• W2078990818 doi "https://doi.org/10.1016/j.cyto.2007.12.007" @default.
• W2078990818 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18289869" @default.
• W2078990818 hasPublicationYear "2008" @default.
• W2078990818 type Work @default.
• W2078990818 sameAs 2078990818 @default.
• W2078990818 citedByCount "33" @default.
• W2078990818 countsByYear W20789908182012 @default.
• W2078990818 countsByYear W20789908182014 @default.
• W2078990818 countsByYear W20789908182015 @default.
• W2078990818 countsByYear W20789908182016 @default.
• W2078990818 countsByYear W20789908182017 @default.
• W2078990818 countsByYear W20789908182018 @default.
• W2078990818 countsByYear W20789908182019 @default.
• W2078990818 countsByYear W20789908182020 @default.
• W2078990818 countsByYear W20789908182021 @default.
• W2078990818 countsByYear W20789908182022 @default.
• W2078990818 crossrefType "journal-article" @default.
• W2078990818 hasAuthorship W2078990818A5000801624 @default.
• W2078990818 hasAuthorship W2078990818A5025546339 @default.
• W2078990818 hasAuthorship W2078990818A5046066980 @default.
• W2078990818 hasAuthorship W2078990818A5061811305 @default.
• W2078990818 hasConcept C121332964 @default.
• W2078990818 hasConcept C126322002 @default.
• W2078990818 hasConcept C142424586 @default.
• W2078990818 hasConcept C159654299 @default.
• W2078990818 hasConcept C163764329 @default.

• next