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- W2078993607 abstract "Long noncoding RNAs (lncRNAs) are a pervasive and recently recognized class of genes. lncRNAs have been proposed to modulate gene expression and nuclear architecture, but their physiological functions are still largely unclear. Several recent efforts to inactivate lncRNA genes in mouse models have shed light on their functions. Different genetic strategies have yielded specific lessons about the roles of lncRNA transcription, the lncRNA transcript itself, and underlying sequence elements. Current results indicate important functions for lncRNAs in organ development, immunity, organismal viability, and in human diseases." @default.
- W2078993607 created "2016-06-24" @default.
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- W2078993607 date "2014-10-01" @default.
- W2078993607 modified "2023-09-29" @default.
- W2078993607 title "Physiological roles of long noncoding RNAs: insight from knockout mice" @default.
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- W2078993607 doi "https://doi.org/10.1016/j.tcb.2014.06.003" @default.
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