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- W2078997029 abstract "Most of the patients with epidermodysplasia verruciformis (EV) were anergic to sensitization to dinitrochlorobenzene (DNCB) and were shown to have a decreased number of T lymphocytes and reduced lymphocyte PHA responsiveness. Preserved cell-mediated immunity (CMI) was found only in the abortive cases of EV infected with human papillomavirus type 3 (HPV-3). CMI was impaired to the same extent in patients with EV induced by HPV-3 and HPV-5, and in EV cases with combined infection with both viruses. In contrast to this, malignant transformation, i.e. of Bowen's carcinoma type, was observed only in the 7 patients infected with HPV-5. This could indicate that malignancy in EV is related rather to the oncogenic potential of HPV-5 type than to the extent of T cell defect that was similar in both EV varieties due to HPV-3 and HPV-5." @default.
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- W2078997029 date "1981-01-01" @default.
- W2078997029 modified "2023-10-18" @default.
- W2078997029 title "T Cell Defect in Patients with Epidermodysplasia verruciformis due to Human Papillomavirus Type 3 and 5" @default.
- W2078997029 doi "https://doi.org/10.1159/000250262" @default.
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