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- W2079002020 abstract "This paper provides the first evidence that the Lathyrus sativus neurotoxin, l-3-oxalylamino-2-aminopropionic Acid (OAP), is toxic when administered intraperitoneally to a primate with a mature bloodbrain barrier. Drowsiness, vomiting, muscle tremors, twitching, convulsions, and death occurred in young male squirrel monkeys (Saimiri sciureus) following injection of 4.26 and 11.4 μmol (0.750 and 2.00 mg) OAP/g body wt. Electroencephalographic changes characteristic of each stage of intoxication were observed. Unchanged OAP was recovered from brain of intoxicated animals. These observations support a possible role for OAP in the etiology of human neurolathyrism, a paralytic disease prevalent among adults in Central India who have consumed large quantities of L. sativus seeds for several months." @default.
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- W2079002020 title "Acute neurotoxicity of the Lathyrus sativus neurotoxin, l-3-oxalylamino-2-aminopropionic acid, in the squirrel monkey" @default.
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- W2079002020 doi "https://doi.org/10.1016/0041-008x(79)90080-2" @default.
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