FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079003398> ?p ?o ?g. }

• W2079003398 endingPage "236" @default.
• W2079003398 startingPage "231" @default.
• W2079003398 abstract "Background and Aims We investigated the behaviour of non-cholesterol sterols, surrogate markers of cholesterol absorption (campesterol and sitosterol) and synthesis (lathosterol), in primary hyperlipemias. Methods and results We studied 53 patients with polygenic hypercholesterolemia (PH), 38 patients with familial combined hyperlipemia (FCH), and 19 age- and sex-matched healthy control subjects. In all participants, plasma sitosterol, campesterol and lathosterol were determined by gas chromatography coupled to mass spectrometry. To correct for the effect of plasma lipid levels, non-cholesterol sterol concentrations were adjusted for plasma cholesterol (102 μmol/mmol cholesterol). Patients with FCH were more frequently men, and had higher body mass index (BMI), fasting glucose, insulin and HOMA-IR. Lathosterol was higher in FCH than in pH or controls (p < 0.05). Campesterol was significantly lower in FCH (p < 0.05), while no differences were found between pH and controls. Sitosterol displayed higher values in pH compared to FCH (p < 0.001) and controls (p < 0.05). Spearman’s rank correlations showed positive correlations of lathosterol with BMI, waist circumference, HOMA-IR, triglycerides, apoprotein B, and a negative one with HDL-cholesterol. Sitosterol had a negative correlation with BMI, waist circumference, HOMA-IR, triglycerides, and a positive one with HDL-cholesterol and apoprotein AI. Multivariate regression analyses showed that cholesterol absorption markers predicted higher HDL-cholesterol levels, while HOMA-IR was a negative predictor of sitosterol and BMI a positive predictor of lathosterol. Conclusions Our findings suggest the occurrence of an increased cholesterol synthesis in FCH, and an increased cholesterol absorption in pH. Markers of cholesterol synthesis cluster with clinical and laboratory markers of obesity and insulin resistance." @default.
• W2079003398 created "2016-06-24" @default.
• W2079003398 creator A5000992130 @default.
• W2079003398 creator A5001000458 @default.
• W2079003398 creator A5012207416 @default.
• W2079003398 creator A5016352385 @default.
• W2079003398 creator A5028270491 @default.
• W2079003398 creator A5039870716 @default.
• W2079003398 creator A5043405846 @default.
• W2079003398 creator A5052191319 @default.
• W2079003398 creator A5054588744 @default.
• W2079003398 date "2012-03-01" @default.
• W2079003398 modified "2023-10-18" @default.
• W2079003398 title "Non-cholesterol sterols in different forms of primary hyperlipemias" @default.
• W2079003398 cites W1487672542 @default.
• W2079003398 cites W1848671298 @default.
• W2079003398 cites W1908881400 @default.
• W2079003398 cites W1973178110 @default.
• W2079003398 cites W1980866997 @default.
• W2079003398 cites W1986884589 @default.
• W2079003398 cites W1988330243 @default.
• W2079003398 cites W2013782817 @default.
• W2079003398 cites W2030634981 @default.
• W2079003398 cites W2034790783 @default.
• W2079003398 cites W2037104620 @default.
• W2079003398 cites W2052992240 @default.
• W2079003398 cites W2064707735 @default.
• W2079003398 cites W2068940630 @default.
• W2079003398 cites W2071115881 @default.
• W2079003398 cites W2073625229 @default.
• W2079003398 cites W2099378835 @default.
• W2079003398 cites W2102620837 @default.
• W2079003398 cites W2107481891 @default.
• W2079003398 cites W2113828666 @default.
• W2079003398 cites W2124315101 @default.
• W2079003398 cites W2125797839 @default.
• W2079003398 cites W2131856792 @default.
• W2079003398 cites W2139767447 @default.
• W2079003398 cites W2154815373 @default.
• W2079003398 cites W2155934503 @default.
• W2079003398 cites W2163802092 @default.
• W2079003398 cites W2188065204 @default.
• W2079003398 cites W2286030148 @default.
• W2079003398 cites W4211051145 @default.
• W2079003398 cites W4238251256 @default.
• W2079003398 cites W4244433315 @default.
• W2079003398 doi "https://doi.org/10.1016/j.numecd.2010.05.010" @default.
• W2079003398 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20708389" @default.
• W2079003398 hasPublicationYear "2012" @default.
• W2079003398 type Work @default.
• W2079003398 sameAs 2079003398 @default.
• W2079003398 citedByCount "23" @default.
• W2079003398 countsByYear W20790033982012 @default.
• W2079003398 countsByYear W20790033982013 @default.
• W2079003398 countsByYear W20790033982014 @default.
• W2079003398 countsByYear W20790033982015 @default.
• W2079003398 countsByYear W20790033982016 @default.
• W2079003398 countsByYear W20790033982017 @default.
• W2079003398 countsByYear W20790033982018 @default.
• W2079003398 countsByYear W20790033982019 @default.
• W2079003398 countsByYear W20790033982020 @default.
• W2079003398 countsByYear W20790033982023 @default.
• W2079003398 crossrefType "journal-article" @default.
• W2079003398 hasAuthorship W2079003398A5000992130 @default.
• W2079003398 hasAuthorship W2079003398A5001000458 @default.
• W2079003398 hasAuthorship W2079003398A5012207416 @default.
• W2079003398 hasAuthorship W2079003398A5016352385 @default.
• W2079003398 hasAuthorship W2079003398A5028270491 @default.
• W2079003398 hasAuthorship W2079003398A5039870716 @default.
• W2079003398 hasAuthorship W2079003398A5043405846 @default.
• W2079003398 hasAuthorship W2079003398A5052191319 @default.
• W2079003398 hasAuthorship W2079003398A5054588744 @default.
• W2079003398 hasConcept C126322002 @default.
• W2079003398 hasConcept C134018914 @default.
• W2079003398 hasConcept C185592680 @default.
• W2079003398 hasConcept C2776193436 @default.
• W2079003398 hasConcept C2777085297 @default.
• W2079003398 hasConcept C2778163477 @default.
• W2079003398 hasConcept C2778718757 @default.
• W2079003398 hasConcept C2780022283 @default.
• W2079003398 hasConcept C2780221984 @default.
• W2079003398 hasConcept C2781471481 @default.
• W2079003398 hasConcept C2910061293 @default.
• W2079003398 hasConcept C71924100 @default.
• W2079003398 hasConceptScore W2079003398C126322002 @default.
• W2079003398 hasConceptScore W2079003398C134018914 @default.
• W2079003398 hasConceptScore W2079003398C185592680 @default.
• W2079003398 hasConceptScore W2079003398C2776193436 @default.
• W2079003398 hasConceptScore W2079003398C2777085297 @default.
• W2079003398 hasConceptScore W2079003398C2778163477 @default.
• W2079003398 hasConceptScore W2079003398C2778718757 @default.
• W2079003398 hasConceptScore W2079003398C2780022283 @default.
• W2079003398 hasConceptScore W2079003398C2780221984 @default.
• W2079003398 hasConceptScore W2079003398C2781471481 @default.
• W2079003398 hasConceptScore W2079003398C2910061293 @default.
• W2079003398 hasConceptScore W2079003398C71924100 @default.
• W2079003398 hasIssue "3" @default.
• W2079003398 hasLocation W20790033981 @default.

• next