Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079005772> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2079005772 endingPage "293" @default.
- W2079005772 startingPage "293" @default.
- W2079005772 abstract "Recently, many studies have focused on the effects of strength training variables manipulation on the activation of intracellular signaling pathways for skeletal muscle hypertrophy. It has been suggested that muscle tension plays a major role in such process via activation of hypertrophy signaling pathways through increase in mechano growth factor (MGF). Eccentric muscle actions (EE) are notorious for imposing a greater amount of tension on the active muscle. In particular, EE performed at high velocities seems to exert an additional effect on muscle tension and thus, on muscle hypertrophy. However, little is known about the effect of EE velocity manipulation on hypertrophy pathways signaling. PURPOSE: To determine the acute effect of low and high velocity EE on muscle hypertrophy signaling proteins (Akt and p70S6K) phosphorylation and MGF mRNA expression. METHODS: Twenty subjects were randomly assigned to either a slow velocity group - 20o/s (ECC20) or fast group - 210o/s (ECC210). Muscle biopsy samples were taken before, immediately after and two hours after the completion of five sets of eight maximal repetitions of knee extension exercise at the designated velocity. Proteins phosphorylation and mRNA expression comparisons were made using two-way ANOVA with repeated measures. RESULTS: Akt and p70S6K protein analysis did not reveal any between or intra groups differences. Akt and p70S6K protein phosphorylation results indicated a main effect for time (p<0.05), with increased phosphorylation values for immediately after and two hours after time points in comparison to baseline values. MGF mRNA analysis did not show any between groups differences but were significantly higher at the two hours post intervention time point when compared to baseline in group ECC20. CONCLUSIONS: The acute manipulation of EE velocity does not seem to differently influence the phosphorylation or expression of the proteins studied." @default.
- W2079005772 created "2016-06-24" @default.
- W2079005772 creator A5003585049 @default.
- W2079005772 creator A5010961378 @default.
- W2079005772 creator A5042325405 @default.
- W2079005772 creator A5066102381 @default.
- W2079005772 creator A5070951517 @default.
- W2079005772 creator A5078419012 @default.
- W2079005772 creator A5079484655 @default.
- W2079005772 creator A5080823938 @default.
- W2079005772 creator A5087374812 @default.
- W2079005772 creator A5091151376 @default.
- W2079005772 date "2010-05-01" @default.
- W2079005772 modified "2023-10-01" @default.
- W2079005772 title "Effect of an Acute Bout of Eccentric Exercise at Different Velocities on Muscle Hypertrophy Signaling" @default.
- W2079005772 doi "https://doi.org/10.1249/01.mss.0000384413.20968.2a" @default.
- W2079005772 hasPublicationYear "2010" @default.
- W2079005772 type Work @default.
- W2079005772 sameAs 2079005772 @default.
- W2079005772 citedByCount "0" @default.
- W2079005772 crossrefType "journal-article" @default.
- W2079005772 hasAuthorship W2079005772A5003585049 @default.
- W2079005772 hasAuthorship W2079005772A5010961378 @default.
- W2079005772 hasAuthorship W2079005772A5042325405 @default.
- W2079005772 hasAuthorship W2079005772A5066102381 @default.
- W2079005772 hasAuthorship W2079005772A5070951517 @default.
- W2079005772 hasAuthorship W2079005772A5078419012 @default.
- W2079005772 hasAuthorship W2079005772A5079484655 @default.
- W2079005772 hasAuthorship W2079005772A5080823938 @default.
- W2079005772 hasAuthorship W2079005772A5087374812 @default.
- W2079005772 hasAuthorship W2079005772A5091151376 @default.
- W2079005772 hasBestOaLocation W20790057721 @default.
- W2079005772 hasConcept C100784341 @default.
- W2079005772 hasConcept C104317684 @default.
- W2079005772 hasConcept C105580179 @default.
- W2079005772 hasConcept C11960822 @default.
- W2079005772 hasConcept C121332964 @default.
- W2079005772 hasConcept C126322002 @default.
- W2079005772 hasConcept C134018914 @default.
- W2079005772 hasConcept C167414201 @default.
- W2079005772 hasConcept C185592680 @default.
- W2079005772 hasConcept C2779959927 @default.
- W2079005772 hasConcept C55493867 @default.
- W2079005772 hasConcept C62478195 @default.
- W2079005772 hasConcept C62520636 @default.
- W2079005772 hasConcept C71924100 @default.
- W2079005772 hasConcept C75217442 @default.
- W2079005772 hasConcept C86803240 @default.
- W2079005772 hasConcept C95444343 @default.
- W2079005772 hasConceptScore W2079005772C100784341 @default.
- W2079005772 hasConceptScore W2079005772C104317684 @default.
- W2079005772 hasConceptScore W2079005772C105580179 @default.
- W2079005772 hasConceptScore W2079005772C11960822 @default.
- W2079005772 hasConceptScore W2079005772C121332964 @default.
- W2079005772 hasConceptScore W2079005772C126322002 @default.
- W2079005772 hasConceptScore W2079005772C134018914 @default.
- W2079005772 hasConceptScore W2079005772C167414201 @default.
- W2079005772 hasConceptScore W2079005772C185592680 @default.
- W2079005772 hasConceptScore W2079005772C2779959927 @default.
- W2079005772 hasConceptScore W2079005772C55493867 @default.
- W2079005772 hasConceptScore W2079005772C62478195 @default.
- W2079005772 hasConceptScore W2079005772C62520636 @default.
- W2079005772 hasConceptScore W2079005772C71924100 @default.
- W2079005772 hasConceptScore W2079005772C75217442 @default.
- W2079005772 hasConceptScore W2079005772C86803240 @default.
- W2079005772 hasConceptScore W2079005772C95444343 @default.
- W2079005772 hasIssue "5" @default.
- W2079005772 hasLocation W20790057721 @default.
- W2079005772 hasLocation W20790057722 @default.
- W2079005772 hasOpenAccess W2079005772 @default.
- W2079005772 hasPrimaryLocation W20790057721 @default.
- W2079005772 hasRelatedWork W1779480512 @default.
- W2079005772 hasRelatedWork W1974568996 @default.
- W2079005772 hasRelatedWork W1989634017 @default.
- W2079005772 hasRelatedWork W2016840789 @default.
- W2079005772 hasRelatedWork W2081376013 @default.
- W2079005772 hasRelatedWork W2309978229 @default.
- W2079005772 hasRelatedWork W2463478234 @default.
- W2079005772 hasRelatedWork W2550488380 @default.
- W2079005772 hasRelatedWork W2748952813 @default.
- W2079005772 hasRelatedWork W3166675052 @default.
- W2079005772 hasVolume "42" @default.
- W2079005772 isParatext "false" @default.
- W2079005772 isRetracted "false" @default.
- W2079005772 magId "2079005772" @default.
- W2079005772 workType "article" @default.