FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079041187> ?p ?o ?g. }

• W2079041187 endingPage "956" @default.
• W2079041187 startingPage "951" @default.
• W2079041187 abstract "Destructive compression tests and finite element analyses were conducted to investigate the biomechanical strength at the graft-endplate interface in anterior cervical fusion.To investigate the effect of endplate thickness, endplate holes, and bone mineral density of the vertebral body on the biomechanical strength of the endplate-graft interface in an anterior interbody fusion of the cervical spine.Subsidence of the graft into the vertebral body is a well-known complication in anterior cervical fusion. However, there is no information in the literature regarding the compressive strength of the graft-endplate interface in relation to the endplate thickness, holes in the endplate, and bone mineral density of the vertebral body.Biomechanical destructive compression tests and finite element analyses were performed in this study. Cervical vertebral bodies (C3-C7) isolated from seven cadaveric cervical spines (age at death 69-86 years, mean 79 years) were used for compression tests. Bone mineral density of each vertebral body was measured using a dual energy radiograph absorptiometry unit. Endplate thickness was measured using three coronal computed tomography images of the middle portion of the vertebral body obtained using a computer-assisted imaging analysis. Then each vertebral body was cut into halves through the horizontal plane. A total of 54 specimens, consisting of one endplate and half of the vertebral body, were obtained after excluding eight vertebrae with gross pathology on plain radiograph. Specimens were assigned to one of three groups with different endplate conditions (Group I, intact; Group II, partial removal; and Group III, complete removal) so that group mean bone mineral density became similar. Each endplate was slowly compressed until failure using an 8-mm-diameter metal indenter, and the load to failure was determined as a maximum force on a recorded force-displacement curve. The effect on the strength of the graft-endplate interface of various hole patterns in the endplate was studied using a finite element technique. The simulatedhole patterns included the following: one large central hole, two lateral holes, two holes in the anterior and posterior portion of the endplate, and four holes evenly distributed from the center of the endplate. Stress distribution in the endplate was predicted in response to an axial compressive force of 110 N, and the elements with von Mises stress greater than 4.0 MPa were determined as failed.The endplate thickness and bone mineral density were similar at all cervical levels, and the superior and inferior endplates had similar thickness at all cervical levels. There was no significant association between bone mineral density and endplate thickness. Load to failure was found to have a significant association with bone mineral density but not with endplate thickness. However, load to failure tends to decrease with incremental removal of the endplate, and load to failure of the specimens with an intact endplate was significantly greater than that of the specimens with no endplate. Finite element model predictions showed significant influence of the hole pattern on the fraction of the upper endplate exposed to fracture stress. A large hole was predicted to be more effective than the other patterns at distributing a compressive load across the remaining area and thus minimizing the potential fracture area.Results of this study suggest that it is important to preserve the endplate as much as possible to prevent graft subsidence into the vertebral body, particularly in patients with poor bone quality. It is preferable to make one central hole rather than multiple smaller holes in the endplate for vascularity of the bone graft because it reduces the surface area exposed to fracture stresses." @default.
• W2079041187 created "2016-06-24" @default.
• W2079041187 creator A5018460235 @default.
• W2079041187 creator A5026974503 @default.
• W2079041187 creator A5035401356 @default.
• W2079041187 creator A5047863588 @default.
• W2079041187 creator A5052672298 @default.
• W2079041187 creator A5067063583 @default.
• W2079041187 creator A5067572808 @default.
• W2079041187 creator A5069437689 @default.
• W2079041187 date "2001-04-01" @default.
• W2079041187 modified "2023-10-01" @default.
• W2079041187 title "Effect of Endplate Conditions and Bone Mineral Density on the Compressive Strength of the Graft–Endplate Interface in Anterior Cervical Spine Fusion" @default.
• W2079041187 cites W1963924838 @default.
• W2079041187 cites W1999138373 @default.
• W2079041187 cites W2005449854 @default.
• W2079041187 cites W2014385482 @default.
• W2079041187 cites W2016361545 @default.
• W2079041187 cites W2029721418 @default.
• W2079041187 cites W2038420290 @default.
• W2079041187 cites W2069751967 @default.
• W2079041187 cites W2096560891 @default.
• W2079041187 cites W2115223136 @default.
• W2079041187 cites W2136841696 @default.
• W2079041187 cites W2149793650 @default.
• W2079041187 cites W2312852841 @default.
• W2079041187 cites W2313628421 @default.
• W2079041187 cites W2320073760 @default.
• W2079041187 cites W2323829795 @default.
• W2079041187 cites W2328674979 @default.
• W2079041187 cites W2336468280 @default.
• W2079041187 doi "https://doi.org/10.1097/00007632-200104150-00021" @default.
• W2079041187 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11317120" @default.
• W2079041187 hasPublicationYear "2001" @default.
• W2079041187 type Work @default.
• W2079041187 sameAs 2079041187 @default.
• W2079041187 citedByCount "164" @default.
• W2079041187 countsByYear W20790411872012 @default.
• W2079041187 countsByYear W20790411872013 @default.
• W2079041187 countsByYear W20790411872014 @default.
• W2079041187 countsByYear W20790411872015 @default.
• W2079041187 countsByYear W20790411872016 @default.
• W2079041187 countsByYear W20790411872017 @default.
• W2079041187 countsByYear W20790411872018 @default.
• W2079041187 countsByYear W20790411872019 @default.
• W2079041187 countsByYear W20790411872020 @default.
• W2079041187 countsByYear W20790411872021 @default.
• W2079041187 countsByYear W20790411872022 @default.
• W2079041187 countsByYear W20790411872023 @default.
• W2079041187 crossrefType "journal-article" @default.
• W2079041187 hasAuthorship W2079041187A5018460235 @default.
• W2079041187 hasAuthorship W2079041187A5026974503 @default.
• W2079041187 hasAuthorship W2079041187A5035401356 @default.
• W2079041187 hasAuthorship W2079041187A5047863588 @default.
• W2079041187 hasAuthorship W2079041187A5052672298 @default.
• W2079041187 hasAuthorship W2079041187A5067063583 @default.
• W2079041187 hasAuthorship W2079041187A5067572808 @default.
• W2079041187 hasAuthorship W2079041187A5069437689 @default.
• W2079041187 hasConcept C105702510 @default.
• W2079041187 hasConcept C13483470 @default.
• W2079041187 hasConcept C141071460 @default.
• W2079041187 hasConcept C142724271 @default.
• W2079041187 hasConcept C159985019 @default.
• W2079041187 hasConcept C175696284 @default.
• W2079041187 hasConcept C180016635 @default.
• W2079041187 hasConcept C192562407 @default.
• W2079041187 hasConcept C2776412215 @default.
• W2079041187 hasConcept C2776541429 @default.
• W2079041187 hasConcept C2776886416 @default.
• W2079041187 hasConcept C2776944266 @default.
• W2079041187 hasConcept C2780375110 @default.
• W2079041187 hasConcept C36454342 @default.
• W2079041187 hasConcept C71924100 @default.
• W2079041187 hasConceptScore W2079041187C105702510 @default.
• W2079041187 hasConceptScore W2079041187C13483470 @default.
• W2079041187 hasConceptScore W2079041187C141071460 @default.
• W2079041187 hasConceptScore W2079041187C142724271 @default.
• W2079041187 hasConceptScore W2079041187C159985019 @default.
• W2079041187 hasConceptScore W2079041187C175696284 @default.
• W2079041187 hasConceptScore W2079041187C180016635 @default.
• W2079041187 hasConceptScore W2079041187C192562407 @default.
• W2079041187 hasConceptScore W2079041187C2776412215 @default.
• W2079041187 hasConceptScore W2079041187C2776541429 @default.
• W2079041187 hasConceptScore W2079041187C2776886416 @default.
• W2079041187 hasConceptScore W2079041187C2776944266 @default.
• W2079041187 hasConceptScore W2079041187C2780375110 @default.
• W2079041187 hasConceptScore W2079041187C36454342 @default.
• W2079041187 hasConceptScore W2079041187C71924100 @default.
• W2079041187 hasIssue "8" @default.
• W2079041187 hasLocation W20790411871 @default.
• W2079041187 hasLocation W20790411872 @default.
• W2079041187 hasOpenAccess W2079041187 @default.
• W2079041187 hasPrimaryLocation W20790411871 @default.
• W2079041187 hasRelatedWork W1749010593 @default.
• W2079041187 hasRelatedWork W1831285444 @default.
• W2079041187 hasRelatedWork W1975464823 @default.
• W2079041187 hasRelatedWork W2008885068 @default.
• W2079041187 hasRelatedWork W2013202750 @default.

• next