Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079043321> ?p ?o ?g. }
- W2079043321 endingPage "208" @default.
- W2079043321 startingPage "199" @default.
- W2079043321 abstract "The nuclear import signal of snRNPs is composed of two essential components, the m3G cap structure of the snRNA and the Sm core NLS carried by the Sm protein core complex. We have previously proposed that, in yeast, this last determinant is represented by a basic-rich protuberance formed by the C-terminal extensions of Sm proteins. In mammals, as well as in other organisms, this component has not yet been precisely defined. Using GFP–Sm fusion constructs and immunolocalization as well as biochemical experiments, we show here that the C-terminal domains of human SmD1 and SmD3 proteins possess nuclear localization properties. Deletions of these domains increase cytoplasmic fluorescence and cytoplasmic localization of GFP–Sm mutant fusion alleles. Our results are consistent with a model in which the Sm core NLS is evolutionarily conserved and composed of a basic-rich protuberance formed by C-terminal domains of different Sm subtypes." @default.
- W2079043321 created "2016-06-24" @default.
- W2079043321 creator A5000822904 @default.
- W2079043321 creator A5003999322 @default.
- W2079043321 creator A5027006482 @default.
- W2079043321 creator A5029587832 @default.
- W2079043321 creator A5036418147 @default.
- W2079043321 date "2004-09-01" @default.
- W2079043321 modified "2023-10-18" @default.
- W2079043321 title "Nuclear localization properties of a conserved protuberance in the Sm core complex" @default.
- W2079043321 cites W1529308217 @default.
- W2079043321 cites W1881929849 @default.
- W2079043321 cites W1904553979 @default.
- W2079043321 cites W1905489680 @default.
- W2079043321 cites W1975584750 @default.
- W2079043321 cites W1976247681 @default.
- W2079043321 cites W1978098648 @default.
- W2079043321 cites W1978550291 @default.
- W2079043321 cites W1993243592 @default.
- W2079043321 cites W2003363387 @default.
- W2079043321 cites W2009989763 @default.
- W2079043321 cites W2017284082 @default.
- W2079043321 cites W2024736109 @default.
- W2079043321 cites W2025730023 @default.
- W2079043321 cites W2028839610 @default.
- W2079043321 cites W2039867172 @default.
- W2079043321 cites W2043059870 @default.
- W2079043321 cites W2045710644 @default.
- W2079043321 cites W2054544162 @default.
- W2079043321 cites W2061993563 @default.
- W2079043321 cites W2078465924 @default.
- W2079043321 cites W2091345758 @default.
- W2079043321 cites W2091533776 @default.
- W2079043321 cites W2093307415 @default.
- W2079043321 cites W2096575861 @default.
- W2079043321 cites W2096650232 @default.
- W2079043321 cites W2098735573 @default.
- W2079043321 cites W2105295436 @default.
- W2079043321 cites W2118485393 @default.
- W2079043321 cites W2121141232 @default.
- W2079043321 cites W2122329067 @default.
- W2079043321 cites W2124049693 @default.
- W2079043321 cites W2128595951 @default.
- W2079043321 cites W2133736734 @default.
- W2079043321 cites W2137891310 @default.
- W2079043321 cites W2138148973 @default.
- W2079043321 cites W2143854031 @default.
- W2079043321 cites W2148718900 @default.
- W2079043321 cites W2151298994 @default.
- W2079043321 cites W2160875554 @default.
- W2079043321 cites W2161391196 @default.
- W2079043321 cites W2163669373 @default.
- W2079043321 cites W2166529547 @default.
- W2079043321 cites W2270729717 @default.
- W2079043321 cites W4233986426 @default.
- W2079043321 cites W4294232809 @default.
- W2079043321 doi "https://doi.org/10.1016/j.yexcr.2004.05.018" @default.
- W2079043321 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15302587" @default.
- W2079043321 hasPublicationYear "2004" @default.
- W2079043321 type Work @default.
- W2079043321 sameAs 2079043321 @default.
- W2079043321 citedByCount "28" @default.
- W2079043321 countsByYear W20790433212012 @default.
- W2079043321 countsByYear W20790433212014 @default.
- W2079043321 countsByYear W20790433212016 @default.
- W2079043321 countsByYear W20790433212017 @default.
- W2079043321 countsByYear W20790433212018 @default.
- W2079043321 countsByYear W20790433212022 @default.
- W2079043321 countsByYear W20790433212023 @default.
- W2079043321 crossrefType "journal-article" @default.
- W2079043321 hasAuthorship W2079043321A5000822904 @default.
- W2079043321 hasAuthorship W2079043321A5003999322 @default.
- W2079043321 hasAuthorship W2079043321A5027006482 @default.
- W2079043321 hasAuthorship W2079043321A5029587832 @default.
- W2079043321 hasAuthorship W2079043321A5036418147 @default.
- W2079043321 hasConcept C104317684 @default.
- W2079043321 hasConcept C123894998 @default.
- W2079043321 hasConcept C142613039 @default.
- W2079043321 hasConcept C143065580 @default.
- W2079043321 hasConcept C186435350 @default.
- W2079043321 hasConcept C190062978 @default.
- W2079043321 hasConcept C29512474 @default.
- W2079043321 hasConcept C40767141 @default.
- W2079043321 hasConcept C49805395 @default.
- W2079043321 hasConcept C54355233 @default.
- W2079043321 hasConcept C54458228 @default.
- W2079043321 hasConcept C67705224 @default.
- W2079043321 hasConcept C68483431 @default.
- W2079043321 hasConcept C86339819 @default.
- W2079043321 hasConcept C86803240 @default.
- W2079043321 hasConcept C95444343 @default.
- W2079043321 hasConceptScore W2079043321C104317684 @default.
- W2079043321 hasConceptScore W2079043321C123894998 @default.
- W2079043321 hasConceptScore W2079043321C142613039 @default.
- W2079043321 hasConceptScore W2079043321C143065580 @default.
- W2079043321 hasConceptScore W2079043321C186435350 @default.
- W2079043321 hasConceptScore W2079043321C190062978 @default.
- W2079043321 hasConceptScore W2079043321C29512474 @default.