Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079049146> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2079049146 endingPage "366" @default.
- W2079049146 startingPage "363" @default.
- W2079049146 abstract "Five anthracycline derivatives, i.e. doxorubicin, epirubicin, pirarubicin, aclarubicin and a new fluorinated anthracycline derivative (ME2303), were tested for antitumour activity in mice with hepatic neoplastic nodules of Lewis lung carcinoma and colon adenocarcinoma 26. Intravenous administrations of pirarubicin and ME2303 on day 4 or days 4, 8 and 12 in mice with hepatic neoplastic nodules of Lewis lung carcinoma rendered more than 50% of mice tumour-free over wide ranges of nontoxic doses, whereas a few mice were cured by treatment with doxorubicin and no mice were cured by treatment with epirubicin or aclarubicin. Moreover, when ME2303 was administered at 50 mg kg-1 on days 7, 11 and 15 to six mice bearing more advanced hepatic tumours, five were cured, while pirarubicin and doxorubicin never achieved cure. Furthermore, in mice with hepatic neoplastic nodules of colon adenocarcinoma 26, ME2303 also showed a marked antitumour effect compared to pirarubicin or doxorubicin. Two or three injections of ME2303 starting from day 7 conferred a greater antitumour effect than did more fractionated or single-dose regimens." @default.
- W2079049146 created "2016-06-24" @default.
- W2079049146 creator A5045566337 @default.
- W2079049146 creator A5061123773 @default.
- W2079049146 creator A5063281154 @default.
- W2079049146 creator A5089007519 @default.
- W2079049146 date "1991-03-01" @default.
- W2079049146 modified "2023-10-09" @default.
- W2079049146 title "Effects of anthracycline derivatives on hepatic neoplastic nodules of Lewis lung carcinoma and colon adenocarcinoma 26" @default.
- W2079049146 cites W1597566405 @default.
- W2079049146 cites W1948096504 @default.
- W2079049146 cites W1970764253 @default.
- W2079049146 cites W1971544331 @default.
- W2079049146 cites W1977076057 @default.
- W2079049146 cites W1981530805 @default.
- W2079049146 cites W1985700863 @default.
- W2079049146 cites W2021290425 @default.
- W2079049146 cites W2074683376 @default.
- W2079049146 cites W2075342858 @default.
- W2079049146 cites W2148781593 @default.
- W2079049146 cites W2418453763 @default.
- W2079049146 doi "https://doi.org/10.1038/bjc.1991.86" @default.
- W2079049146 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1971864" @default.
- W2079049146 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2003977" @default.
- W2079049146 hasPublicationYear "1991" @default.
- W2079049146 type Work @default.
- W2079049146 sameAs 2079049146 @default.
- W2079049146 citedByCount "4" @default.
- W2079049146 crossrefType "journal-article" @default.
- W2079049146 hasAuthorship W2079049146A5045566337 @default.
- W2079049146 hasAuthorship W2079049146A5061123773 @default.
- W2079049146 hasAuthorship W2079049146A5063281154 @default.
- W2079049146 hasAuthorship W2079049146A5089007519 @default.
- W2079049146 hasBestOaLocation W20790491462 @default.
- W2079049146 hasConcept C121608353 @default.
- W2079049146 hasConcept C126322002 @default.
- W2079049146 hasConcept C142724271 @default.
- W2079049146 hasConcept C2776085618 @default.
- W2079049146 hasConcept C2776694085 @default.
- W2079049146 hasConcept C2776755627 @default.
- W2079049146 hasConcept C2776802502 @default.
- W2079049146 hasConcept C2777714996 @default.
- W2079049146 hasConcept C2777847059 @default.
- W2079049146 hasConcept C2779013556 @default.
- W2079049146 hasConcept C2780835546 @default.
- W2079049146 hasConcept C2780847677 @default.
- W2079049146 hasConcept C2781182431 @default.
- W2079049146 hasConcept C2781303535 @default.
- W2079049146 hasConcept C530470458 @default.
- W2079049146 hasConcept C71924100 @default.
- W2079049146 hasConceptScore W2079049146C121608353 @default.
- W2079049146 hasConceptScore W2079049146C126322002 @default.
- W2079049146 hasConceptScore W2079049146C142724271 @default.
- W2079049146 hasConceptScore W2079049146C2776085618 @default.
- W2079049146 hasConceptScore W2079049146C2776694085 @default.
- W2079049146 hasConceptScore W2079049146C2776755627 @default.
- W2079049146 hasConceptScore W2079049146C2776802502 @default.
- W2079049146 hasConceptScore W2079049146C2777714996 @default.
- W2079049146 hasConceptScore W2079049146C2777847059 @default.
- W2079049146 hasConceptScore W2079049146C2779013556 @default.
- W2079049146 hasConceptScore W2079049146C2780835546 @default.
- W2079049146 hasConceptScore W2079049146C2780847677 @default.
- W2079049146 hasConceptScore W2079049146C2781182431 @default.
- W2079049146 hasConceptScore W2079049146C2781303535 @default.
- W2079049146 hasConceptScore W2079049146C530470458 @default.
- W2079049146 hasConceptScore W2079049146C71924100 @default.
- W2079049146 hasIssue "3" @default.
- W2079049146 hasLocation W20790491461 @default.
- W2079049146 hasLocation W20790491462 @default.
- W2079049146 hasLocation W20790491463 @default.
- W2079049146 hasLocation W20790491464 @default.
- W2079049146 hasOpenAccess W2079049146 @default.
- W2079049146 hasPrimaryLocation W20790491461 @default.
- W2079049146 hasRelatedWork W1002865637 @default.
- W2079049146 hasRelatedWork W187025307 @default.
- W2079049146 hasRelatedWork W2079049146 @default.
- W2079049146 hasRelatedWork W2093278494 @default.
- W2079049146 hasRelatedWork W2367264910 @default.
- W2079049146 hasRelatedWork W2410698257 @default.
- W2079049146 hasRelatedWork W2425248660 @default.
- W2079049146 hasRelatedWork W2998568045 @default.
- W2079049146 hasRelatedWork W3101806148 @default.
- W2079049146 hasRelatedWork W3152993703 @default.
- W2079049146 hasVolume "63" @default.
- W2079049146 isParatext "false" @default.
- W2079049146 isRetracted "false" @default.
- W2079049146 magId "2079049146" @default.
- W2079049146 workType "article" @default.