Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079061307> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2079061307 endingPage "741" @default.
- W2079061307 startingPage "737" @default.
- W2079061307 abstract "This study was designed to determine if low doses of oral sodium phenylbutyrate (SPB) induce hemoglobin F (HbF) synthesis in children with hemoglobin SS (HbSS). We treated 8 children with HbSS over a period of 5-30 weeks. The initial dose (1.0 g/d) was increased weekly (by 1.0 g/d) until F-reticulocytes doubled. All patients showed an increase in F-reticulocytes (P = 0.002) that was dose-dependent (P = 0.001). Three of 5 patients who continued oral SPB for more than 10 weeks had substantial increases in HbF. We conclude that lower dose SPB is effective in inducing HbF synthesis in some children with HbSS. Further trials are warranted to determine the optimal treatment regimen." @default.
- W2079061307 created "2016-06-24" @default.
- W2079061307 creator A5005567441 @default.
- W2079061307 creator A5009862383 @default.
- W2079061307 creator A5050695217 @default.
- W2079061307 creator A5059779868 @default.
- W2079061307 creator A5061685890 @default.
- W2079061307 creator A5079372083 @default.
- W2079061307 date "2002-12-01" @default.
- W2079061307 modified "2023-10-16" @default.
- W2079061307 title "Induction of Fetal Hemoglobin Synthesis in Children With Sickle Cell Anemia on Low-Dose Oral Sodium Phenylbutyrate Therapy" @default.
- W2079061307 cites W1244925421 @default.
- W2079061307 cites W1488281450 @default.
- W2079061307 cites W1719867626 @default.
- W2079061307 cites W176375325 @default.
- W2079061307 cites W1966313798 @default.
- W2079061307 cites W1972799369 @default.
- W2079061307 cites W1987037884 @default.
- W2079061307 cites W2019018139 @default.
- W2079061307 cites W2020520804 @default.
- W2079061307 cites W2049129790 @default.
- W2079061307 cites W2056046551 @default.
- W2079061307 cites W2085732078 @default.
- W2079061307 cites W2168300377 @default.
- W2079061307 cites W2313541759 @default.
- W2079061307 cites W2313825712 @default.
- W2079061307 cites W2322074970 @default.
- W2079061307 cites W2326476344 @default.
- W2079061307 cites W2334263927 @default.
- W2079061307 cites W2399444701 @default.
- W2079061307 cites W4250085880 @default.
- W2079061307 cites W4252113783 @default.
- W2079061307 doi "https://doi.org/10.1097/00043426-200212000-00011" @default.
- W2079061307 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12468915" @default.
- W2079061307 hasPublicationYear "2002" @default.
- W2079061307 type Work @default.
- W2079061307 sameAs 2079061307 @default.
- W2079061307 citedByCount "32" @default.
- W2079061307 countsByYear W20790613072012 @default.
- W2079061307 countsByYear W20790613072014 @default.
- W2079061307 countsByYear W20790613072015 @default.
- W2079061307 countsByYear W20790613072017 @default.
- W2079061307 countsByYear W20790613072020 @default.
- W2079061307 crossrefType "journal-article" @default.
- W2079061307 hasAuthorship W2079061307A5005567441 @default.
- W2079061307 hasAuthorship W2079061307A5009862383 @default.
- W2079061307 hasAuthorship W2079061307A5050695217 @default.
- W2079061307 hasAuthorship W2079061307A5059779868 @default.
- W2079061307 hasAuthorship W2079061307A5061685890 @default.
- W2079061307 hasAuthorship W2079061307A5079372083 @default.
- W2079061307 hasConcept C126322002 @default.
- W2079061307 hasConcept C172680121 @default.
- W2079061307 hasConcept C2776317666 @default.
- W2079061307 hasConcept C2778248108 @default.
- W2079061307 hasConcept C2778620579 @default.
- W2079061307 hasConcept C2778917026 @default.
- W2079061307 hasConcept C2779134260 @default.
- W2079061307 hasConcept C2779234561 @default.
- W2079061307 hasConcept C2781413609 @default.
- W2079061307 hasConcept C2909310144 @default.
- W2079061307 hasConcept C54355233 @default.
- W2079061307 hasConcept C71924100 @default.
- W2079061307 hasConcept C86803240 @default.
- W2079061307 hasConcept C90924648 @default.
- W2079061307 hasConceptScore W2079061307C126322002 @default.
- W2079061307 hasConceptScore W2079061307C172680121 @default.
- W2079061307 hasConceptScore W2079061307C2776317666 @default.
- W2079061307 hasConceptScore W2079061307C2778248108 @default.
- W2079061307 hasConceptScore W2079061307C2778620579 @default.
- W2079061307 hasConceptScore W2079061307C2778917026 @default.
- W2079061307 hasConceptScore W2079061307C2779134260 @default.
- W2079061307 hasConceptScore W2079061307C2779234561 @default.
- W2079061307 hasConceptScore W2079061307C2781413609 @default.
- W2079061307 hasConceptScore W2079061307C2909310144 @default.
- W2079061307 hasConceptScore W2079061307C54355233 @default.
- W2079061307 hasConceptScore W2079061307C71924100 @default.
- W2079061307 hasConceptScore W2079061307C86803240 @default.
- W2079061307 hasConceptScore W2079061307C90924648 @default.
- W2079061307 hasIssue "9" @default.
- W2079061307 hasLocation W20790613071 @default.
- W2079061307 hasLocation W20790613072 @default.
- W2079061307 hasOpenAccess W2079061307 @default.
- W2079061307 hasPrimaryLocation W20790613071 @default.
- W2079061307 hasRelatedWork W1920239827 @default.
- W2079061307 hasRelatedWork W1969917888 @default.
- W2079061307 hasRelatedWork W1984664967 @default.
- W2079061307 hasRelatedWork W2015924858 @default.
- W2079061307 hasRelatedWork W2026873950 @default.
- W2079061307 hasRelatedWork W2055893366 @default.
- W2079061307 hasRelatedWork W2070488645 @default.
- W2079061307 hasRelatedWork W2071610315 @default.
- W2079061307 hasRelatedWork W2257228458 @default.
- W2079061307 hasRelatedWork W4242968924 @default.
- W2079061307 hasVolume "24" @default.
- W2079061307 isParatext "false" @default.
- W2079061307 isRetracted "false" @default.
- W2079061307 magId "2079061307" @default.
- W2079061307 workType "article" @default.