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• W2079062478 abstract "The pressure-clamp technique, used in conjunction with patch-clamp techniques, allows the application of precise pressure/suction waveforms to membrane patches and whole cells. Using step perturbations in pressure, it allows rapid relaxation measurements of the latency, turn-on, turn-off and adaptation kinetics of mechanosensitive membrane ion channels. The pressure-clamp technique also provides the ability to apply gentle and reproducible sealing protocols to establish tight seals and thereby minimize membrane-cytoskeleton disruption which can otherwise alter channel properties." @default.
• W2079062478 created "2016-06-24" @default.
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• W2079062478 date "1993-09-01" @default.
• W2079062478 modified "2023-10-15" @default.
• W2079062478 title "Pressure-clamp technique for measurement of the relaxation kinetics of mechanosensitive channels" @default.
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• W2079062478 doi "https://doi.org/10.1016/0166-2236(93)90089-5" @default.
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