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- W2079062607 abstract "Abstract The dissociation constants of (4-amino-1-hydroxybutylidene)bisphosphonic (alendronic) acid, (3-(dimethylamino)-1-hydroxypropylidene)bisphosphonic (olpadronic) acid and (3-amino-1-hydroxypropylidene)bisphosphonic (pamidronic) acid were obtained in aqueous solutions (0.10 M KCl) and micellar solutions of cetylpyridinium chloride (0.10 M CPC) at 25.0°C. With the exception of the third dissociation constant of alendronic acid, the dissociation constants of alendronic, olpadronic and pamidronic acids in aqueous solutions matched literature data. The possibility of sodium alendronate determination by acid-base titration by NaOH solution was theoretically grounded on the basis of re-evaluated data of alendronic acid dissociation constants." @default.
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- W2079062607 date "2009-03-01" @default.
- W2079062607 modified "2023-09-24" @default.
- W2079062607 title "Re-evaluated data of dissociation constants of alendronic, pamidronic and olpadronic acids" @default.
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- W2079062607 doi "https://doi.org/10.2478/s11532-008-0099-z" @default.
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