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- W2079063388 abstract "The response of astrocytes to pharmacological alterations of the serotonin (5-HT) content of the dorsal area dentata was studied by immunocytochemistry for S100 beta. Stereological analysis revealed changes in the density of astrocytic elements in conditions of 5-HT depletion and elevated 5-HT levels. There was a direct relationship between the expression of S100 beta and the level of 5-HT in the hippocampal formation. Thus when 5-HT was reduced by PCPA treatment, S100 beta immunoreactivity was also reduced. The converse of these observations was obtained in cases where the 5-HT levels were increased by fluoxetine administration. These immunocytochemical data are consistent with previous reports of the response of astrocytes to 5-HT in vitro." @default.
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- W2079063388 date "1993-12-01" @default.
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- W2079063388 title "Hippocampal serotonin levels influence the expression of S100β detected by immunocytochemistry" @default.
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- W2079063388 doi "https://doi.org/10.1016/0006-8993(93)91195-x" @default.
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