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- W2079063732 endingPage "4016" @default.
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- W2079063732 abstract "Here we study the binding behavior of perylenediimide () derivatives to a hydrophobic pocket created inside DNA and their photochemical properties capable of designing a light-up fluorescent sensor for short single-stranded DNA or RNA. The perylenediimide derivative with alkoxy groups () suppressing electron transfer quenching was examined. The bound randomly to DNA showed negligible fluorescence due to the aggregation-induced quenching, whereas the bound to the pocket as a monomeric form showed more than 100-fold fluorescence enhancement. Switching the binding states of the corresponded to a change in the fluorescence response for the hybridization event, which allowed us to design a fluorescent sensor of nucleic acids with a nanomolar detection limit." @default.
- W2079063732 created "2016-06-24" @default.
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- W2079063732 date "2014-06-16" @default.
- W2079063732 modified "2023-09-27" @default.
- W2079063732 title "Light-up fluorescent probes utilizing binding behavior of perylenediimide derivatives to a hydrophobic pocket within DNA" @default.
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- W2079063732 doi "https://doi.org/10.1039/c4an00493k" @default.
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