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- W2079074254 abstract "Here the authors find that the kinetics of synaptic vesicle endocytosis are widely variable across different neurons and is stochastic regardless of neuronal firing histories or number of presynaptic boutons. Although individual nerve terminals from the same neuron often differ in neurotransmitter release characteristics, the extent to which endocytic retrieval of synaptic vesicle components differs is unknown. We used high-fidelity optical recordings to undertake a large-scale analysis of endocytosis kinetics of individual boutons in hippocampal rat neurons. Our data indicate that endocytosis kinetics do not differ substantially across boutons from the same cell but instead appear to be controlled at a cell-wide level." @default.
- W2079074254 created "2016-06-24" @default.
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- W2079074254 date "2011-05-29" @default.
- W2079074254 modified "2023-10-12" @default.
- W2079074254 title "Synaptic vesicle retrieval time is a cell-wide rather than individual-synapse property" @default.
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- W2079074254 doi "https://doi.org/10.1038/nn.2828" @default.
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