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- W2079077102 abstract "Focal amplifications in 6p21 containing the VEGFA locus occur in 7%-10% of hepatocellular carcinoma (HCC). A recent paper describes how VEGF-A stimulates paracrine secretion of hepatocyte growth factor by stromal cells, which induces tumor progression. HCC patients with VEGFA amplification are distinctly sensitive to sorafenib." @default.
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- W2079077102 date "2014-05-01" @default.
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- W2079077102 title "Focal Gains of VEGFA: Candidate Predictors of Sorafenib Response in Hepatocellular Carcinoma" @default.
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- W2079077102 doi "https://doi.org/10.1016/j.ccr.2014.04.019" @default.
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