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• W2079077464 abstract "We evaluated the progression of conduction system and myocardial disease in 17 asymptomatic myotonic dystrophy patients by clinical evaluation, electrocardiography, vector cardiography, and echocardiography. An exercise test was done in 10 patients. After 8 years, a follow-up study of 12 of the 17 original patients was done with a similar protocol. During this period, 2 patients died: one of sudden death while the other had acute left ventricular failure. In our first control study, we found EKG abnormalities in IS of our patients, consisting mostly of conduction defects or pseudonecrotic patterns. In our second control, all patients had conduction system disease and, in addition, 3 of them had premature ventricular beats. One patient developed dilated cardiomyopathy. In 6 patients, structural involvement of the right ventricle was found. We conclude that even in asymptomatic myotonic dystrophy patients a conduction system deficit is present and progresses, and cardiac death may occur in about 12% of these patients." @default.
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• W2079077464 date "1988-04-01" @default.
• W2079077464 modified "2023-09-26" @default.
• W2079077464 title "The natural history of cardiac involvement in myotonic dystrophy: An eight-year follow-up in 17 patients" @default.
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• W2079077464 doi "https://doi.org/10.1002/clc.4960110407" @default.
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