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- W2079079323 abstract "Abstract The relation of left ventricular size, as estimated with echocardiography, to mortality was evaluated in three groups of infants with severe left ventricular outflow obstruction. Group I consisted of 17 patients with combined aortic and mitral stenosis or atresia associated with definite hypoplasia of the left ventricle. Group II consisted of eight patients with the primary diagnosis of severe aortic stenosis. Group III consisted of 12 patients with severe coarctation of the aorta. The left ventricular enddiastolic dimension measured with M mode echocardiography and the cross-sectional area of the left ventricular cavity as seen in the parasternal long axis view of the two dimensional echocardiogram were used as indexes of left ventricular volume. All patients with symptomatic outflow obstruction and a left ventricular end-diastolic dimension of less than 13 mm died in infancy. However, five patients with a hypoplastic left ventricle proved at angiography or at autopsy, or both, were found to have a ventricular end-diastolic dimension of 13 mm or greater. Two dimensional echocardiography showed that the left ventricle in these patients was foreshortened and spherical in shape. The cross-sectional area of the left ventricle of each patient in group I was less than 1.6 cm 2 . This was below the range of cross-sectional areas found in a group of normal infants (1.8 to 3.5 cm 2 ± 2 standard deviations about the mean). Three patients in groups II and III had a slightly reduced left ventricular area (1.7 cm 2 ) and none of these patients survived infancy. Measurement of the cross-sectional area of the left ventricle is a useful method of determining left ventricular size in infants suspected of having the hypoplastic left ventricle syndrome. Patients who have reduced left ventricular volume as assessed by this technique are at very great risk even if surgical relief of the outflow obstruction is attempted." @default.
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- W2079079323 date "1981-11-01" @default.
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- W2079079323 title "Relation of the echocardiographic estimate of left ventricular size to mortality in infants with severe left ventricular outflow obstruction" @default.
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- W2079079323 doi "https://doi.org/10.1016/0002-9149(81)90354-4" @default.
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