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- W2079085809 abstract "We investigated the wind-up phenomenon of the flexor reflex in adult and aged rats. The sural nerve was stimulated at C-fiber strength and reflex activity was recorded from the semitendinosus muscle. The wind-up rate, the increment rate of the C-fiber response (i.e. activity from 100 to 600 ms after stimulation) by successive stimuli (five train pulses), was decreased exponentially with increasing stimulus intervals from 3 to 20 s. The time constant of the decay for the aged rats was 9.2+/-3.2 s (mean+/-SD), which was significantly longer than for the adult rats (6.4+/-2.9 s). The findings indicate that the effects of C-fiber activation on the spinal nociceptive pathways attenuate more slowly in aged rats as compared with adult rats." @default.
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- W2079085809 date "2001-05-01" @default.
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- W2079085809 title "Temporal facilitation of the flexor reflex induced by C-fiber activity: comparison between adult and aged rats" @default.
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- W2079085809 doi "https://doi.org/10.1016/s0304-3940(01)01761-x" @default.
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